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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHKB All Species: 17.88
Human Site: T205 Identified Species: 39.33
UniProt: Q9Y259 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y259 NP_005189.2 395 45271 T205 Q I Q D L P P T G L P E M N L
Chimpanzee Pan troglodytes XP_001144399 395 45239 T205 Q I Q D L P P T G L P E M N L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848257 395 45274 T205 Q I Q D L P P T D L P Q M N L
Cat Felis silvestris
Mouse Mus musculus O55229 394 45108 T205 Q I Q D L P S T S L P Q M N L
Rat Rattus norvegicus O54783 394 45082 T205 Q I Q D L P S T S L P Q M N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520038 436 47973 S217 G S N V H G R S P I P F Y P A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093482 451 51710 V266 Q V K T L K F V R E A H I K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54352 518 59544 L250 K A E T Q N F L L L H T Y G L
Honey Bee Apis mellifera XP_624492 379 44310 I194 N V N M I R I I D L D H E I K
Nematode Worm Caenorhab. elegans P46558 371 42767 S186 S E H P K K I S M D D L Y K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20485 582 66298 K276 Q W L R T I E K V D Q W V G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 90.3 N.A. 85.8 84.8 N.A. 38.9 N.A. N.A. 52.9 N.A. 20.6 44 27.3 N.A.
Protein Similarity: 100 99.7 N.A. 94.1 N.A. 92.9 92.1 N.A. 49.7 N.A. N.A. 68 N.A. 38 61.7 45.8 N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 80 N.A. 6.6 N.A. N.A. 13.3 N.A. 13.3 6.6 0 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 20 N.A. N.A. 33.3 N.A. 26.6 20 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 46 0 0 0 0 19 19 19 0 0 0 10 % D
% Glu: 0 10 10 0 0 0 10 0 0 10 0 19 10 0 10 % E
% Phe: 0 0 0 0 0 0 19 0 0 0 0 10 0 0 0 % F
% Gly: 10 0 0 0 0 10 0 0 19 0 0 0 0 19 0 % G
% His: 0 0 10 0 10 0 0 0 0 0 10 19 0 0 0 % H
% Ile: 0 46 0 0 10 10 19 10 0 10 0 0 10 10 0 % I
% Lys: 10 0 10 0 10 19 0 10 0 0 0 0 0 19 19 % K
% Leu: 0 0 10 0 55 0 0 10 10 64 0 10 0 0 55 % L
% Met: 0 0 0 10 0 0 0 0 10 0 0 0 46 0 0 % M
% Asn: 10 0 19 0 0 10 0 0 0 0 0 0 0 46 0 % N
% Pro: 0 0 0 10 0 46 28 0 10 0 55 0 0 10 0 % P
% Gln: 64 0 46 0 10 0 0 0 0 0 10 28 0 0 0 % Q
% Arg: 0 0 0 10 0 10 10 0 10 0 0 0 0 0 0 % R
% Ser: 10 10 0 0 0 0 19 19 19 0 0 0 0 0 0 % S
% Thr: 0 0 0 19 10 0 0 46 0 0 0 10 0 0 0 % T
% Val: 0 19 0 10 0 0 0 10 10 0 0 0 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _