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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3L
All Species:
25.15
Human Site:
S10
Identified Species:
39.52
UniProt:
Q9Y262
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y262
NP_057175.1
564
66727
S10
Y
P
A
D
D
Y
E
S
E
A
A
Y
D
P
Y
Chimpanzee
Pan troglodytes
A5A6M4
564
66678
S10
Y
P
A
D
D
Y
E
S
E
A
A
Y
D
P
Y
Rhesus Macaque
Macaca mulatta
XP_001090065
580
67561
S53
Y
P
A
D
D
Y
E
S
E
A
A
Y
D
P
Y
Dog
Lupus familis
XP_850423
564
66678
S10
Y
P
A
D
D
Y
E
S
E
A
A
Y
D
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZY1
564
66594
S10
Y
P
A
D
D
Y
E
S
E
A
A
Y
D
P
Y
Rat
Rattus norvegicus
NP_001029306
382
45064
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514662
564
66751
T10
Y
P
T
E
E
Y
D
T
E
A
A
Y
D
P
Y
Chicken
Gallus gallus
Q5F428
564
66664
N10
Y
P
G
E
D
Y
D
N
D
A
A
Y
D
P
Y
Frog
Xenopus laevis
Q8AVJ0
562
66504
Y12
K
E
D
Y
D
S
S
Y
D
P
Y
S
Y
Q
A
Zebra Danio
Brachydanio rerio
Q7T2A5
576
67975
Y12
A
E
E
E
D
V
N
Y
D
P
Y
S
Y
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU4
539
63205
N10
G
G
D
E
Y
A
T
N
S
D
Y
Y
D
D
Y
Honey Bee
Apis mellifera
XP_624438
538
63386
A10
D
D
Y
N
E
Y
D
A
Y
D
D
Y
G
P
P
Nematode Worm
Caenorhab. elegans
Q95QW0
537
62458
S10
R
R
V
E
F
D
L
S
T
E
D
H
S
D
R
Sea Urchin
Strong. purpuratus
XP_795841
550
64272
K10
Y
N
Q
G
K
D
Y
K
E
S
K
Y
D
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SB62
474
54448
Conservation
Percent
Protein Identity:
100
99.8
92.5
99.8
N.A.
99.1
67.5
N.A.
98.5
97.8
94.1
89.7
N.A.
53.9
58.3
40.5
62.2
Protein Similarity:
100
99.8
92.5
99.8
N.A.
99.6
67.7
N.A.
99.4
99.4
97.6
94.7
N.A.
71.9
72.1
63.1
75.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
66.6
66.6
6.6
13.3
N.A.
20
20
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
93.3
93.3
13.3
26.6
N.A.
33.3
46.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
42.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
34
0
0
7
0
7
0
47
47
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
14
34
54
14
20
0
20
14
14
0
60
14
0
% D
% Glu:
0
14
7
34
14
0
34
0
47
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
7
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
7
0
0
7
0
0
7
0
0
7
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
7
14
0
0
0
0
0
0
7
% N
% Pro:
0
47
0
0
0
0
0
0
0
14
0
0
0
60
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
7
7
40
7
7
0
14
7
0
0
% S
% Thr:
0
0
7
0
0
0
7
7
7
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
7
7
7
54
7
14
7
0
20
67
14
0
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _