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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3L
All Species:
30.3
Human Site:
Y23
Identified Species:
47.62
UniProt:
Q9Y262
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y262
NP_057175.1
564
66727
Y23
P
Y
A
Y
P
S
D
Y
D
M
H
T
G
D
P
Chimpanzee
Pan troglodytes
A5A6M4
564
66678
Y23
P
Y
A
Y
P
S
D
Y
D
M
H
T
G
D
P
Rhesus Macaque
Macaca mulatta
XP_001090065
580
67561
Y66
P
Y
A
Y
P
S
D
Y
D
M
H
T
G
D
P
Dog
Lupus familis
XP_850423
564
66678
Y23
P
Y
A
Y
P
G
D
Y
D
M
H
T
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZY1
564
66594
Y23
P
Y
A
Y
P
G
D
Y
D
M
H
T
G
D
P
Rat
Rattus norvegicus
NP_001029306
382
45064
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514662
564
66751
Y23
P
Y
T
Y
P
G
D
Y
D
M
H
T
G
D
P
Chicken
Gallus gallus
Q5F428
564
66664
Y23
P
Y
A
Y
S
N
D
Y
D
M
H
T
G
D
P
Frog
Xenopus laevis
Q8AVJ0
562
66504
T25
Q
A
D
Y
D
G
H
T
G
D
P
K
Q
D
L
Zebra Danio
Brachydanio rerio
Q7T2A5
576
67975
T25
P
N
D
Y
D
Y
H
T
G
D
P
K
A
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU4
539
63205
P23
D
Y
A
H
T
G
D
P
Q
L
D
M
E
Y
E
Honey Bee
Apis mellifera
XP_624438
538
63386
Q23
P
P
D
V
H
S
D
Q
Y
D
R
L
G
Y
R
Nematode Worm
Caenorhab. elegans
Q95QW0
537
62458
F23
D
R
R
R
T
N
T
F
S
S
S
A
D
E
D
Sea Urchin
Strong. purpuratus
XP_795841
550
64272
Y23
K
Y
G
Y
D
N
R
Y
E
S
H
T
G
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SB62
474
54448
Conservation
Percent
Protein Identity:
100
99.8
92.5
99.8
N.A.
99.1
67.5
N.A.
98.5
97.8
94.1
89.7
N.A.
53.9
58.3
40.5
62.2
Protein Similarity:
100
99.8
92.5
99.8
N.A.
99.6
67.7
N.A.
99.4
99.4
97.6
94.7
N.A.
71.9
72.1
63.1
75.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
86.6
86.6
13.3
20
N.A.
20
26.6
0
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
0
N.A.
86.6
93.3
13.3
20
N.A.
33.3
26.6
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
42.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
47
0
0
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
20
0
20
0
60
0
47
20
7
0
7
67
7
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
0
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
34
0
0
14
0
0
0
60
0
0
% G
% His:
0
0
0
7
7
0
14
0
0
0
54
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
47
0
7
0
0
0
% M
% Asn:
0
7
0
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
7
0
0
40
0
0
7
0
0
14
0
0
0
54
% P
% Gln:
7
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
7
7
7
0
0
7
0
0
0
7
0
0
0
7
% R
% Ser:
0
0
0
0
7
27
0
0
7
14
7
0
0
0
0
% S
% Thr:
0
0
7
0
14
0
7
14
0
0
0
54
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
67
0
7
0
54
7
0
0
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _