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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3L
All Species:
32.12
Human Site:
Y415
Identified Species:
50.48
UniProt:
Q9Y262
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y262
NP_057175.1
564
66727
Y415
V
Y
E
E
L
F
S
Y
S
C
P
K
F
L
S
Chimpanzee
Pan troglodytes
A5A6M4
564
66678
Y415
V
Y
E
E
L
F
S
Y
S
C
P
K
F
L
S
Rhesus Macaque
Macaca mulatta
XP_001090065
580
67561
D439
Q
L
R
E
K
Y
G
D
K
M
L
R
M
Q
K
Dog
Lupus familis
XP_850423
564
66678
Y415
V
Y
E
E
L
F
S
Y
S
C
P
K
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZY1
564
66594
Y415
V
Y
E
E
L
F
S
Y
A
C
P
K
F
L
S
Rat
Rattus norvegicus
NP_001029306
382
45064
V242
C
P
K
F
L
S
P
V
V
P
N
Y
D
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514662
564
66751
Y415
V
Y
E
E
L
F
S
Y
S
C
P
K
F
L
S
Chicken
Gallus gallus
Q5F428
564
66664
Y415
V
Y
E
E
L
F
S
Y
A
C
P
K
F
L
S
Frog
Xenopus laevis
Q8AVJ0
562
66504
Y413
I
Y
E
E
L
F
N
Y
A
C
P
K
F
L
S
Zebra Danio
Brachydanio rerio
Q7T2A5
576
67975
F414
V
F
E
E
L
F
S
F
A
C
P
K
F
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU4
539
63205
P395
A
C
P
R
F
V
S
P
C
P
P
A
V
D
A
Honey Bee
Apis mellifera
XP_624438
538
63386
N394
L
T
P
P
N
P
D
N
P
N
E
D
Y
V
R
Nematode Worm
Caenorhab. elegans
Q95QW0
537
62458
L393
A
T
G
C
P
K
F
L
S
P
T
T
V
V
Y
Sea Urchin
Strong. purpuratus
XP_795841
550
64272
S401
T
F
E
E
C
F
S
S
A
C
P
R
F
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SB62
474
54448
Y334
G
P
E
A
L
P
I
Y
E
E
L
F
R
T
A
Conservation
Percent
Protein Identity:
100
99.8
92.5
99.8
N.A.
99.1
67.5
N.A.
98.5
97.8
94.1
89.7
N.A.
53.9
58.3
40.5
62.2
Protein Similarity:
100
99.8
92.5
99.8
N.A.
99.6
67.7
N.A.
99.4
99.4
97.6
94.7
N.A.
71.9
72.1
63.1
75.8
P-Site Identity:
100
100
6.6
100
N.A.
93.3
6.6
N.A.
100
93.3
80
80
N.A.
13.3
0
6.6
60
P-Site Similarity:
100
100
20
100
N.A.
100
13.3
N.A.
100
100
100
100
N.A.
20
20
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
42.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
0
0
0
0
34
0
0
7
0
0
14
% A
% Cys:
7
7
0
7
7
0
0
0
7
60
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
7
0
0
0
7
7
7
0
% D
% Glu:
0
0
67
67
0
0
0
0
7
7
7
0
0
0
0
% E
% Phe:
0
14
0
7
7
60
7
7
0
0
0
7
60
0
0
% F
% Gly:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
7
7
0
0
7
0
0
54
0
0
7
% K
% Leu:
7
7
0
0
67
0
0
7
0
0
14
0
0
60
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
0
0
0
0
7
0
7
7
0
7
7
0
0
7
0
% N
% Pro:
0
14
14
7
7
14
7
7
7
20
67
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
0
14
7
0
7
% R
% Ser:
0
0
0
0
0
7
60
7
34
0
0
0
0
0
60
% S
% Thr:
7
14
0
0
0
0
0
0
0
0
7
7
0
7
0
% T
% Val:
47
0
0
0
0
7
0
7
7
0
0
0
14
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
0
0
0
7
0
54
0
0
0
7
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _