KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3L
All Species:
27.27
Human Site:
Y72
Identified Species:
42.86
UniProt:
Q9Y262
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y262
NP_057175.1
564
66727
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Chimpanzee
Pan troglodytes
A5A6M4
564
66678
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Rhesus Macaque
Macaca mulatta
XP_001090065
580
67561
Y115
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Dog
Lupus familis
XP_850423
564
66678
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZY1
564
66594
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Rat
Rattus norvegicus
NP_001029306
382
45064
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514662
564
66751
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Chicken
Gallus gallus
Q5F428
564
66664
Y72
D
L
I
D
Q
K
V
Y
E
L
Q
A
S
R
V
Frog
Xenopus laevis
Q8AVJ0
562
66504
A74
Q
K
V
Y
E
L
Q
A
S
R
V
S
S
D
L
Zebra Danio
Brachydanio rerio
Q7T2A5
576
67975
Q74
D
Q
K
V
Y
E
L
Q
A
N
R
V
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU4
539
63205
I72
Y
E
N
T
F
P
Q
I
S
D
H
H
F
D
K
Honey Bee
Apis mellifera
XP_624438
538
63386
D72
K
I
S
E
Q
L
F
D
K
S
S
W
P
D
T
Nematode Worm
Caenorhab. elegans
Q95QW0
537
62458
R72
D
L
T
E
R
F
F
R
D
R
M
W
P
D
E
Sea Urchin
Strong. purpuratus
XP_795841
550
64272
V72
G
H
I
R
D
K
N
V
Y
D
I
N
H
C
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SB62
474
54448
A13
Q
A
Q
A
P
A
R
A
I
D
P
D
S
D
V
Conservation
Percent
Protein Identity:
100
99.8
92.5
99.8
N.A.
99.1
67.5
N.A.
98.5
97.8
94.1
89.7
N.A.
53.9
58.3
40.5
62.2
Protein Similarity:
100
99.8
92.5
99.8
N.A.
99.6
67.7
N.A.
99.4
99.4
97.6
94.7
N.A.
71.9
72.1
63.1
75.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
100
6.6
13.3
N.A.
0
6.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
100
33.3
33.3
N.A.
0
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
42.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
7
0
14
7
0
0
47
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
60
0
0
47
7
0
0
7
7
20
0
7
0
34
0
% D
% Glu:
0
7
0
14
7
7
0
0
47
0
0
0
0
0
14
% E
% Phe:
0
0
0
0
7
7
14
0
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
7
7
7
0
0
% H
% Ile:
0
7
54
0
0
0
0
7
7
0
7
0
0
0
0
% I
% Lys:
7
7
7
0
0
54
0
0
7
0
0
0
0
0
7
% K
% Leu:
0
54
0
0
0
14
7
0
0
47
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
7
7
0
0
0
0
7
0
14
0
0
% P
% Gln:
14
7
7
0
54
0
14
7
0
0
47
0
0
0
0
% Q
% Arg:
0
0
0
7
7
0
7
7
0
14
7
0
0
47
0
% R
% Ser:
0
0
7
0
0
0
0
0
14
7
7
7
67
7
0
% S
% Thr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
7
7
0
0
47
7
0
0
7
7
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% W
% Tyr:
7
0
0
7
7
0
0
47
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _