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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLAA All Species: 43.33
Human Site: S406 Identified Species: 79.44
UniProt: Q9Y263 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y263 NP_001026859.1 795 87157 S406 K E F D Y V F S I D V N E G G
Chimpanzee Pan troglodytes XP_520517 795 87109 S406 K E F D Y V F S I D V N E G G
Rhesus Macaque Macaca mulatta XP_001105698 795 87274 S406 K E F D Y V F S I D V N E G G
Dog Lupus familis XP_531963 772 84828 S406 K E F D Y V F S I D V N E G G
Cat Felis silvestris
Mouse Mus musculus P27612 794 87217 S406 K E F D Y V F S I D V N E G G
Rat Rattus norvegicus P54319 795 87065 S406 K E F D Y V F S I D V N E G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505972 373 41498 C18 V F K L L K K C S R I Q V F Q
Chicken Gallus gallus XP_424941 794 87233 T406 K E Y D Y V F T I D V N E S G
Frog Xenopus laevis Q6GM65 799 87851 T412 K E Y D Y V F T I D V N E S G
Zebra Danio Brachydanio rerio NP_997855 798 86218 T404 K E Y D F V F T I D V N E G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524666 787 85733 S411 K E Y D F V F S V D I S D T E
Honey Bee Apis mellifera XP_392743 782 86559 S419 I E Y D Y V F S V D I Q D G I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36037 715 79487 W360 H Q F S N S S W K K V G D V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.8 93.5 N.A. 93.9 94.5 N.A. 37.6 79.5 73.3 66.6 N.A. 37.2 40.2 N.A. N.A.
Protein Similarity: 100 99.8 99.3 94.7 N.A. 96.9 97.2 N.A. 41.7 87.3 84.6 81.5 N.A. 55.2 59.8 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 80 80 80 N.A. 46.6 53.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 93.3 93.3 100 N.A. 86.6 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 85 0 0 0 0 0 85 0 0 24 0 0 % D
% Glu: 0 85 0 0 0 0 0 0 0 0 0 0 70 0 8 % E
% Phe: 0 8 54 0 16 0 85 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 62 70 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 70 0 24 0 0 0 8 % I
% Lys: 77 0 8 0 0 8 8 0 8 8 0 0 0 0 0 % K
% Leu: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 70 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 16 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 8 8 62 8 0 0 8 0 16 0 % S
% Thr: 0 0 0 0 0 0 0 24 0 0 0 0 0 8 0 % T
% Val: 8 0 0 0 0 85 0 0 16 0 77 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 39 0 70 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _