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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLAA All Species: 20.3
Human Site: S504 Identified Species: 37.22
UniProt: Q9Y263 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y263 NP_001026859.1 795 87157 S504 A G R Y V P G S A S M G T T M
Chimpanzee Pan troglodytes XP_520517 795 87109 S504 A G R Y V P G S A S M G T T M
Rhesus Macaque Macaca mulatta XP_001105698 795 87274 S504 A G R Y V P G S T S M G T T M
Dog Lupus familis XP_531963 772 84828 S498 V D P F T G N S A Y R S A A S
Cat Felis silvestris
Mouse Mus musculus P27612 794 87217 S504 A G R Y M P G S A G M D T T M
Rat Rattus norvegicus P54319 795 87065 S504 A G R Y M P G S A G M D T T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505972 373 41498 K107 A Y R S A T F K T V N I Y F P
Chicken Gallus gallus XP_424941 794 87233 G503 G A G R Y V P G S A S N V V A
Frog Xenopus laevis Q6GM65 799 87851 S508 N R Y V P G S S L Q S D Y S A
Zebra Danio Brachydanio rerio NP_997855 798 86218 T504 Y I P G S G S T G T A P S G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524666 787 85733 G503 G N V D P F T G A S S Y S T A
Honey Bee Apis mellifera XP_392743 782 86559 S509 E F T R S T A S N S S D A S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36037 715 79487 D449 I S L D Q P N D N A S S S A V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.8 93.5 N.A. 93.9 94.5 N.A. 37.6 79.5 73.3 66.6 N.A. 37.2 40.2 N.A. N.A.
Protein Similarity: 100 99.8 99.3 94.7 N.A. 96.9 97.2 N.A. 41.7 87.3 84.6 81.5 N.A. 55.2 59.8 N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 80 80 N.A. 13.3 0 6.6 0 N.A. 20 13.3 N.A. N.A.
P-Site Similarity: 100 100 93.3 20 N.A. 86.6 86.6 N.A. 13.3 13.3 13.3 20 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 8 0 0 8 0 8 0 47 16 8 0 16 16 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 16 0 0 0 8 0 0 0 31 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 8 0 8 8 0 0 0 0 0 0 8 0 % F
% Gly: 16 39 8 8 0 24 39 16 8 16 0 24 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 16 0 0 0 0 0 39 0 0 0 39 % M
% Asn: 8 8 0 0 0 0 16 0 16 0 8 8 0 0 0 % N
% Pro: 0 0 16 0 16 47 8 0 0 0 0 8 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 8 47 16 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 8 0 8 16 0 16 62 8 39 39 16 24 16 8 % S
% Thr: 0 0 8 0 8 16 8 8 16 8 0 0 39 47 0 % T
% Val: 8 0 8 8 24 8 0 0 0 8 0 0 8 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 8 39 8 0 0 0 0 8 0 8 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _