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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLAA All Species: 17.88
Human Site: T490 Identified Species: 32.78
UniProt: Q9Y263 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y263 NP_001026859.1 795 87157 T490 G S S N T L P T A D P F T G A
Chimpanzee Pan troglodytes XP_520517 795 87109 T490 G S S N T L P T A D P F T G A
Rhesus Macaque Macaca mulatta XP_001105698 795 87274 T490 G S S N T L P T A D P F T G A
Dog Lupus familis XP_531963 772 84828 M484 Y V P G S A N M G T T M A G V
Cat Felis silvestris
Mouse Mus musculus P27612 794 87217 T490 G P S N T V Q T A D P F T G A
Rat Rattus norvegicus P54319 795 87065 T490 G P S N T V Q T A D P F T G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505972 373 41498 P93 I Y S I S V F P N C E G N A A
Chicken Gallus gallus XP_424941 794 87233 P489 S S L S N T A P A A D P F T G
Frog Xenopus laevis Q6GM65 799 87851 A494 S S T D N N G A D P F T G G N
Zebra Danio Brachydanio rerio NP_997855 798 86218 P490 G Q Q F G A D P F T G A G R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524666 787 85733 N489 R Y V P G S S N T N M G S G G
Honey Bee Apis mellifera XP_392743 782 86559 T495 S R Y I P Q S T T N T V S H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36037 715 79487 I435 R D Q V V Q F I L K N T N G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.8 93.5 N.A. 93.9 94.5 N.A. 37.6 79.5 73.3 66.6 N.A. 37.2 40.2 N.A. N.A.
Protein Similarity: 100 99.8 99.3 94.7 N.A. 96.9 97.2 N.A. 41.7 87.3 84.6 81.5 N.A. 55.2 59.8 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 80 80 N.A. 13.3 13.3 13.3 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 86.6 86.6 N.A. 26.6 20 26.6 6.6 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 8 8 47 8 0 8 8 8 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 8 0 8 39 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 8 0 0 16 0 8 0 8 39 8 0 0 % F
% Gly: 47 0 0 8 16 0 8 0 8 0 8 16 16 70 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 16 0 0 0 8 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 24 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 8 0 0 0 % M
% Asn: 0 0 0 39 16 8 8 8 8 16 8 0 16 0 8 % N
% Pro: 0 16 8 8 8 0 24 24 0 8 39 8 0 0 0 % P
% Gln: 0 8 16 0 0 16 16 0 0 0 0 0 0 0 0 % Q
% Arg: 16 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 24 39 47 8 16 8 16 0 0 0 0 0 16 0 0 % S
% Thr: 0 0 8 0 39 8 0 47 16 16 16 16 39 8 0 % T
% Val: 0 8 8 8 8 24 0 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 16 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _