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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPT4
All Species:
7.58
Human Site:
S218
Identified Species:
18.52
UniProt:
Q9Y264
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y264
NP_057069.1
503
56849
S218
E
E
L
A
S
I
L
S
K
K
A
K
L
L
N
Chimpanzee
Pan troglodytes
XP_001145488
495
56844
E211
I
Q
L
Q
S
I
K
E
E
K
D
Q
L
Q
V
Rhesus Macaque
Macaca mulatta
XP_001112522
503
57002
S218
E
E
L
A
S
I
L
S
K
K
A
K
L
L
N
Dog
Lupus familis
XP_852012
498
55980
G218
A
E
L
A
S
L
R
G
E
K
E
R
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVH6
509
57787
E227
A
Q
L
N
S
L
Q
E
K
R
E
Q
L
H
S
Rat
Rattus norvegicus
O35460
497
57442
E214
E
E
L
D
T
L
K
E
E
K
E
N
L
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505935
496
56838
D211
V
Q
L
Q
S
I
K
D
E
K
D
Q
L
Q
V
Chicken
Gallus gallus
P14448
741
82420
R274
T
D
H
V
A
E
A
R
G
D
S
S
P
S
H
Frog
Xenopus laevis
Q5XK91
457
51018
Q191
E
G
Q
S
H
V
A
Q
L
G
S
S
V
S
E
Zebra Danio
Brachydanio rerio
NP_571888
513
58342
T225
Q
E
L
E
S
L
R
T
E
K
S
D
L
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.3
95.2
69.7
N.A.
55.4
44.3
N.A.
46.1
24.2
28
46
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.1
96.4
81.7
N.A.
69.1
66.4
N.A.
67
41.4
46.1
66
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
40
N.A.
26.6
33.3
N.A.
33.3
0
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
100
60
N.A.
60
53.3
N.A.
53.3
26.6
33.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
30
10
0
20
0
0
0
20
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
10
0
10
20
10
0
0
0
% D
% Glu:
40
50
0
10
0
10
0
30
50
0
30
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
10
10
0
0
0
0
10
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
10
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
30
0
30
70
0
20
0
0
0
% K
% Leu:
0
0
80
0
0
40
20
0
10
0
0
0
80
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
30
10
20
0
0
10
10
0
0
0
30
0
40
0
% Q
% Arg:
0
0
0
0
0
0
20
10
0
10
0
10
0
10
10
% R
% Ser:
0
0
0
10
70
0
0
20
0
0
30
20
0
20
10
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
10
0
10
0
0
0
0
0
0
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _