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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUVBL1
All Species:
38.79
Human Site:
T381
Identified Species:
71.11
UniProt:
Q9Y265
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y265
NP_003698.1
456
50228
T381
I
I
K
I
R
A
Q
T
E
G
I
N
I
S
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533718
471
52044
T396
I
I
K
I
R
A
Q
T
E
G
I
N
I
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTM5
463
51094
E377
I
L
R
I
R
C
E
E
E
D
V
E
M
S
E
Rat
Rattus norvegicus
P60123
456
50195
T381
I
I
K
I
R
A
Q
T
E
G
I
N
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006138
456
50178
T381
I
I
K
L
R
A
Q
T
E
G
I
N
I
C
E
Frog
Xenopus laevis
Q9DE26
456
50340
T381
I
I
K
I
R
A
Q
T
E
G
I
N
I
S
E
Zebra Danio
Brachydanio rerio
Q8AWW7
456
50349
T381
I
I
K
I
R
A
Q
T
E
G
L
N
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH07
456
50224
T381
I
I
K
L
R
A
Q
T
E
G
L
Q
L
E
E
Honey Bee
Apis mellifera
XP_393051
456
50061
T381
I
V
K
L
R
A
T
T
E
G
L
Q
I
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782589
457
50214
T382
I
L
R
I
R
A
Q
T
E
S
I
Q
I
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197625
458
50305
V383
I
I
A
I
R
A
Q
V
E
E
L
T
V
D
E
Baker's Yeast
Sacchar. cerevisiae
Q03940
463
50435
T389
T
I
I
E
R
R
A
T
V
E
R
L
Q
V
E
Red Bread Mold
Neurospora crassa
Q8WZS3
458
49793
T382
I
V
K
I
R
S
T
T
E
G
V
K
I
T
E
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
96.8
N.A.
42.5
99.7
N.A.
N.A.
96.2
95.1
92.1
N.A.
79.3
82.6
N.A.
85.3
Protein Similarity:
100
N.A.
N.A.
96.8
N.A.
66
100
N.A.
N.A.
98.6
99.3
98.2
N.A.
91.2
92.9
N.A.
93.8
P-Site Identity:
100
N.A.
N.A.
100
N.A.
40
100
N.A.
N.A.
86.6
100
93.3
N.A.
66.6
53.3
N.A.
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
73.3
100
N.A.
N.A.
93.3
100
100
N.A.
86.6
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
72.7
67.6
68.3
Protein Similarity:
N.A.
N.A.
N.A.
88.4
82.5
85.3
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
77
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
16
% D
% Glu:
0
0
0
8
0
0
8
8
93
16
0
8
0
24
85
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
93
70
8
70
0
0
0
0
0
0
47
0
70
0
0
% I
% Lys:
0
0
70
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
16
0
24
0
0
0
0
0
0
31
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
70
0
0
0
0
24
8
0
0
% Q
% Arg:
0
0
16
0
100
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
8
0
0
0
47
0
% S
% Thr:
8
0
0
0
0
0
16
85
0
0
0
8
0
8
0
% T
% Val:
0
16
0
0
0
0
0
8
8
0
16
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _