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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC22A14 All Species: 11.82
Human Site: S33 Identified Species: 23.64
UniProt: Q9Y267 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y267 NP_004794.2 594 66716 S33 A G H P H S W S L E M L L R R
Chimpanzee Pan troglodytes XP_001171631 634 70957 S33 A G H P H S R S L E M L L R R
Rhesus Macaque Macaca mulatta XP_001087218 647 72399 S55 A G H P H S W S L E M L L H R
Dog Lupus familis XP_542707 697 78287 S90 P E H I H S P S L E M L L R R
Cat Felis silvestris
Mouse Mus musculus Q6A4L0 551 60722 L31 L M G I P N F L A A F F I F G
Rat Rattus norvegicus O35956 551 60748 A32 V A P L L L M A S H N T L Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521203 462 51596
Chicken Gallus gallus XP_418528 520 57060 L8 M S G I G E N L K A A G E F G
Frog Xenopus laevis Q66J52 552 61646 A32 S L P V F M L A S H N L M Q N
Zebra Danio Brachydanio rerio Q6NYN7 560 61953 L29 T L L S M P I L M M A S H N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCA2 548 60985 A28 Y Y L L C L P A I V C A F H K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U539 585 65444 V29 K P P D F D F V L E Q V G N Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 82 58.8 N.A. 35 27.1 N.A. 35 37 28.7 27.6 N.A. 26.2 N.A. 23.2 N.A.
Protein Similarity: 100 92.1 85.7 71.7 N.A. 56 49.4 N.A. 51.8 56 49.1 49.1 N.A. 47.8 N.A. 43.4 N.A.
P-Site Identity: 100 93.3 93.3 73.3 N.A. 0 6.6 N.A. 0 0 6.6 0 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 93.3 93.3 73.3 N.A. 20 20 N.A. 0 0 33.3 6.6 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 0 0 0 0 0 25 9 17 17 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 9 0 0 0 42 0 0 9 0 0 % E
% Phe: 0 0 0 0 17 0 17 0 0 0 9 9 9 17 0 % F
% Gly: 0 25 17 0 9 0 0 0 0 0 0 9 9 0 17 % G
% His: 0 0 34 0 34 0 0 0 0 17 0 0 9 17 0 % H
% Ile: 0 0 0 25 0 0 9 0 9 0 0 0 9 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % K
% Leu: 9 17 17 17 9 17 9 25 42 0 0 42 42 0 9 % L
% Met: 9 9 0 0 9 9 9 0 9 9 34 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 0 0 17 0 0 17 17 % N
% Pro: 9 9 25 25 9 9 17 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 17 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 0 25 34 % R
% Ser: 9 9 0 9 0 34 0 34 17 0 0 9 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 9 0 0 9 0 0 0 9 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _