KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A14
All Species:
4.55
Human Site:
T586
Identified Species:
9.09
UniProt:
Q9Y267
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y267
NP_004794.2
594
66716
T586
N
K
V
K
D
M
K
T
K
E
T
S
S
D
D
Chimpanzee
Pan troglodytes
XP_001171631
634
70957
T586
N
K
V
K
D
I
K
T
K
E
T
S
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001087218
647
72399
P608
N
K
V
K
D
M
T
P
E
D
T
S
S
D
D
Dog
Lupus familis
XP_542707
697
78287
F644
R
N
V
A
E
E
L
F
T
K
E
V
V
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4L0
551
60722
V543
G
R
T
S
S
V
R
V
A
V
V
K
S
S
Y
Rat
Rattus norvegicus
O35956
551
60748
M539
Q
E
Q
Q
K
Q
M
M
P
L
Q
A
S
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521203
462
51596
E455
I
S
Y
I
Y
S
A
E
L
F
P
T
I
I
T
Chicken
Gallus gallus
XP_418528
520
57060
Q513
A
D
G
T
E
G
G
Q
P
T
A
V
V
S
D
Frog
Xenopus laevis
Q66J52
552
61646
E542
S
A
K
I
P
L
K
E
T
E
L
Y
N
M
K
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
A547
L
P
E
K
L
D
L
A
M
K
D
P
S
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
E538
A
E
E
G
G
T
Q
E
L
S
G
M
L
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
G552
K
K
P
E
P
D
S
G
M
F
T
Q
A
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
82
58.8
N.A.
35
27.1
N.A.
35
37
28.7
27.6
N.A.
26.2
N.A.
23.2
N.A.
Protein Similarity:
100
92.1
85.7
71.7
N.A.
56
49.4
N.A.
51.8
56
49.1
49.1
N.A.
47.8
N.A.
43.4
N.A.
P-Site Identity:
100
93.3
73.3
13.3
N.A.
6.6
6.6
N.A.
0
6.6
13.3
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
86.6
26.6
N.A.
26.6
26.6
N.A.
6.6
13.3
33.3
20
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
9
0
0
9
9
9
0
9
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
25
17
0
0
0
9
9
0
0
25
42
% D
% Glu:
0
17
17
9
17
9
0
25
9
25
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% F
% Gly:
9
0
9
9
9
9
9
9
0
0
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
17
0
9
0
0
0
0
0
0
9
9
0
% I
% Lys:
9
34
9
34
9
0
25
0
17
17
0
9
0
0
17
% K
% Leu:
9
0
0
0
9
9
17
0
17
9
9
0
9
0
0
% L
% Met:
0
0
0
0
0
17
9
9
17
0
0
9
0
9
0
% M
% Asn:
25
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
9
9
0
17
0
0
9
17
0
9
9
0
0
0
% P
% Gln:
9
0
9
9
0
9
9
9
0
0
9
9
0
0
9
% Q
% Arg:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
9
9
0
0
9
0
25
50
17
0
% S
% Thr:
0
0
9
9
0
9
9
17
17
9
34
9
0
9
9
% T
% Val:
0
0
34
0
0
9
0
9
0
9
9
17
17
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _