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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFL2
All Species:
39.7
Human Site:
Y82
Identified Species:
72.78
UniProt:
Q9Y281
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y281
NP_068733.1
166
18737
Y82
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Chimpanzee
Pan troglodytes
XP_509898
289
31289
Y205
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Rhesus Macaque
Macaca mulatta
XP_001082579
317
33147
Y233
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Dog
Lupus familis
XP_851281
242
25771
Y100
L
P
D
K
D
C
R
Y
A
L
Y
D
A
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P45591
166
18691
Y82
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Rat
Rattus norvegicus
P45592
166
18514
Y82
L
P
D
K
D
C
R
Y
A
L
Y
D
A
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512147
253
27590
Y169
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Chicken
Gallus gallus
P21566
166
18643
Y82
L
P
L
N
D
C
R
Y
A
L
Y
D
A
T
Y
Frog
Xenopus laevis
Q5XHH8
167
18839
Y82
L
P
L
D
D
C
R
Y
G
L
Y
D
A
T
Y
Zebra Danio
Brachydanio rerio
NP_991263
166
18550
Y82
L
P
L
N
D
C
R
Y
G
L
Y
D
A
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41764
139
15881
S59
S
Y
D
D
F
T
N
S
L
P
E
N
D
C
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQ81
140
16323
I60
Y
E
D
F
T
R
S
I
P
E
D
E
C
R
Y
Baker's Yeast
Sacchar. cerevisiae
Q03048
143
15882
L63
K
L
P
E
N
D
C
L
Y
A
I
Y
D
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
52.3
52.8
N.A.
99.4
81.3
N.A.
64.8
98.1
87.4
89.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.4
52.3
60.3
N.A.
100
90.3
N.A.
65.2
99.4
93.4
95.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
86.6
N.A.
100
100
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
86.6
N.A.
100
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
31.9
N.A.
30.7
36.7
N.A.
Protein Similarity:
N.A.
46.9
N.A.
54.2
53.6
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
62
8
0
0
77
0
0
% A
% Cys:
0
0
0
0
0
77
8
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
31
16
77
8
0
0
0
0
8
77
16
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
8
8
8
0
0
8
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
77
8
62
0
0
0
0
8
8
77
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
54
8
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
77
8
0
0
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
77
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
0
77
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
77
8
0
77
8
0
0
85
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _