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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC3 All Species: 30.61
Human Site: Y255 Identified Species: 51.79
UniProt: Q9Y282 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y282 NP_057050.1 383 43222 Y255 H L S F G E D Y P G I V N P L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098982 383 43176 Y255 H L S F G E D Y P G I V N P L
Dog Lupus familis XP_534403 342 38661 D222 P G I V N P L D R T N V T A P
Cat Felis silvestris
Mouse Mus musculus Q9CQE7 383 43190 Y255 H L S F G E D Y P G I V N P L
Rat Rattus norvegicus NP_001100003 383 43205 Y255 H L S F G E D Y P G I V N P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417322 361 40924 Y233 H L S F G R D Y P G I V N P L
Frog Xenopus laevis Q66KH2 389 44134 Y261 H L S F G K D Y P G L V N P L
Zebra Danio Brachydanio rerio Q803I2 383 43121 Y255 H L S F G K D Y P G I V N P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393819 384 43027 I256 H L S F G L N I P G K T N P M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792057 387 43799 Y257 T L S F G M E Y P G M E N P L
Poplar Tree Populus trichocarpa XP_002306582 386 43428 F259 R L T F G E Y F P G V V N P L
Maize Zea mays NP_001148795 386 43436 F259 R L S F G E Y F P G V V N P L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001154394 386 43340 F259 R L T Y G D Y F P G V V N P L
Baker's Yeast Sacchar. cerevisiae P39727 415 46217 V281 K R H G G A V V A T S P L D G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 86.4 N.A. 98.1 98.6 N.A. N.A. 83.2 83.8 87.4 N.A. N.A. 52 N.A. 68.2
Protein Similarity: 100 N.A. 100 87.9 N.A. 100 100 N.A. N.A. 88.5 92.2 95.5 N.A. N.A. 69.5 N.A. 82.9
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. N.A. 93.3 86.6 93.3 N.A. N.A. 60 N.A. 66.6
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. N.A. 73.3 N.A. 80
Percent
Protein Identity: 54.6 52.5 N.A. 52.3 37.3 N.A.
Protein Similarity: 71.7 70.9 N.A. 71.2 53.7 N.A.
P-Site Identity: 66.6 73.3 N.A. 53.3 6.6 N.A.
P-Site Similarity: 86.6 86.6 N.A. 86.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 50 8 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 43 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 79 0 0 0 22 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 93 0 0 0 0 86 0 0 0 0 8 % G
% His: 58 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 43 0 0 0 0 % I
% Lys: 8 0 0 0 0 15 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 86 0 0 0 8 8 0 0 0 8 0 8 0 79 % L
% Met: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 0 8 0 8 0 0 0 8 0 86 0 0 % N
% Pro: 8 0 0 0 0 8 0 0 86 0 0 8 0 86 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 22 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 72 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 8 0 15 0 0 0 0 0 0 15 0 8 8 0 0 % T
% Val: 0 0 0 8 0 0 8 8 0 0 22 79 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 22 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _