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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERGIC3 All Species: 17.27
Human Site: Y59 Identified Species: 29.23
UniProt: Q9Y282 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y282 NP_057050.1 383 43222 Y59 T E V H P E L Y V D K S R G D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098982 383 43176 Y59 T E V H P E L Y V D K S R G D
Dog Lupus familis XP_534403 342 38661 A51 S I D A M D V A G E Q Q L D V
Cat Felis silvestris
Mouse Mus musculus Q9CQE7 383 43190 Y59 T E V H P E L Y V D K S R G D
Rat Rattus norvegicus NP_001100003 383 43205 Y59 T E V H P E L Y V D K S R G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417322 361 40924 A61 C A Y L S I D A M D V A G E Q
Frog Xenopus laevis Q66KH2 389 44134 F59 K E V Y P E L F V D K S R G D
Zebra Danio Brachydanio rerio Q803I2 383 43121 F59 K E V H P E L F V D T S R G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393819 384 43027 F58 P T L S E E L F V D T S R G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792057 387 43799 Y62 K E V I P E L Y V D A T R G E
Poplar Tree Populus trichocarpa XP_002306582 386 43428 V60 A V T E T K L V V D T S R G E
Maize Zea mays NP_001148795 386 43436 R60 A V T E T T L R V D T S R G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001154394 386 43340 I60 T V T E T K L I V D T S R G E
Baker's Yeast Sacchar. cerevisiae P39727 415 46217 V58 V V T R P Q L V V D R D R H A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 86.4 N.A. 98.1 98.6 N.A. N.A. 83.2 83.8 87.4 N.A. N.A. 52 N.A. 68.2
Protein Similarity: 100 N.A. 100 87.9 N.A. 100 100 N.A. N.A. 88.5 92.2 95.5 N.A. N.A. 69.5 N.A. 82.9
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. N.A. 6.6 80 80 N.A. N.A. 46.6 N.A. 66.6
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 100 N.A. N.A. 20 93.3 86.6 N.A. N.A. 60 N.A. 80
Percent
Protein Identity: 54.6 52.5 N.A. 52.3 37.3 N.A.
Protein Similarity: 71.7 70.9 N.A. 71.2 53.7 N.A.
P-Site Identity: 40 40 N.A. 46.6 33.3 N.A.
P-Site Similarity: 53.3 46.6 N.A. 60 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 8 0 0 0 15 0 0 8 8 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 8 0 0 93 0 8 0 8 43 % D
% Glu: 0 50 0 22 8 58 0 0 0 8 0 0 0 8 29 % E
% Phe: 0 0 0 0 0 0 0 22 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 8 79 0 % G
% His: 0 0 0 36 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 8 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 22 0 0 0 0 15 0 0 0 0 36 0 0 0 0 % K
% Leu: 0 0 8 8 0 0 86 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 58 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 8 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 8 0 0 8 0 86 0 0 % R
% Ser: 8 0 0 8 8 0 0 0 0 0 0 72 0 0 8 % S
% Thr: 36 8 29 0 22 8 0 0 0 0 36 8 0 0 0 % T
% Val: 8 29 50 0 0 0 8 15 86 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 36 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _