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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INVS
All Species:
8.79
Human Site:
S665
Identified Species:
21.48
UniProt:
Q9Y283
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y283
NP_055240.2
1065
117826
S665
S
R
G
S
P
G
G
S
L
G
G
A
L
Q
K
Chimpanzee
Pan troglodytes
XP_528516
1065
117759
S665
S
R
G
S
P
G
G
S
L
G
G
A
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001112073
1064
117665
S665
S
R
G
S
P
G
G
S
L
G
R
A
L
Q
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O89019
1062
117110
G668
P
E
H
S
R
L
P
G
R
C
P
G
R
A
S
Rat
Rattus norvegicus
Q8VHK2
1430
150329
A889
H
S
L
N
R
Y
A
A
S
D
S
E
P
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506939
1106
120372
P687
R
G
E
S
P
G
V
P
G
G
T
T
A
G
R
Chicken
Gallus gallus
Q8UVC3
1106
122535
C671
S
R
G
S
P
K
A
C
R
S
K
G
S
P
K
Frog
Xenopus laevis
Q71S21
1002
111890
V631
E
Q
I
I
K
N
E
V
V
H
E
W
Q
G
E
Zebra Danio
Brachydanio rerio
Q8UVC1
1021
113016
K638
V
K
D
S
V
A
A
K
G
H
K
H
K
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203798
1139
120682
R754
T
P
L
H
F
A
S
R
S
G
H
I
D
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.6
N.A.
N.A.
80.5
20
N.A.
66
65.6
48.7
54.3
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
99.8
98.5
N.A.
N.A.
86
31.9
N.A.
74.7
75.2
61.5
66.7
N.A.
N.A.
N.A.
N.A.
36.9
P-Site Identity:
100
100
93.3
N.A.
N.A.
6.6
0
N.A.
26.6
40
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
6.6
26.6
N.A.
33.3
40
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
30
10
0
0
0
30
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
10
10
10
0
0
0
10
0
0
0
10
10
0
10
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
40
0
0
40
30
10
20
50
20
20
0
20
0
% G
% His:
10
0
10
10
0
0
0
0
0
20
10
10
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
10
10
0
10
0
0
20
0
10
10
40
% K
% Leu:
0
0
20
0
0
10
0
0
30
0
0
0
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
50
0
10
10
0
0
10
0
10
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
10
30
0
% Q
% Arg:
10
40
0
0
20
0
0
10
20
0
10
0
10
0
20
% R
% Ser:
40
10
0
70
0
0
10
30
20
10
10
0
10
0
20
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
10
0
0
0
10
0
10
10
10
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _