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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INVS
All Species:
9.09
Human Site:
S746
Identified Species:
22.22
UniProt:
Q9Y283
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y283
NP_055240.2
1065
117826
S746
K
G
F
V
K
Q
P
S
C
I
R
V
A
G
P
Chimpanzee
Pan troglodytes
XP_528516
1065
117759
S746
K
G
F
V
K
Q
P
S
C
I
R
V
A
G
P
Rhesus Macaque
Macaca mulatta
XP_001112073
1064
117665
S746
K
G
F
V
K
Q
P
S
C
I
R
V
A
G
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O89019
1062
117110
L750
P
S
S
A
R
Q
P
L
C
T
G
S
G
R
P
Rat
Rattus norvegicus
Q8VHK2
1430
150329
A987
V
R
A
Q
R
R
R
A
S
D
L
A
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506939
1106
120372
D782
C
R
T
A
R
R
R
D
A
T
E
D
Q
R
A
Chicken
Gallus gallus
Q8UVC3
1106
122535
Q773
A
G
E
K
T
R
D
Q
S
L
S
S
S
G
N
Frog
Xenopus laevis
Q71S21
1002
111890
P711
S
P
L
G
N
E
I
P
K
N
M
Y
W
D
D
Zebra Danio
Brachydanio rerio
Q8UVC1
1021
113016
R720
C
G
S
A
N
E
R
R
S
P
A
G
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203798
1139
120682
G836
I
Y
L
I
E
D
R
G
A
P
I
D
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.6
N.A.
N.A.
80.5
20
N.A.
66
65.6
48.7
54.3
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
99.8
98.5
N.A.
N.A.
86
31.9
N.A.
74.7
75.2
61.5
66.7
N.A.
N.A.
N.A.
N.A.
36.9
P-Site Identity:
100
100
100
N.A.
N.A.
26.6
0
N.A.
0
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
33.3
20
N.A.
13.3
33.3
6.6
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
30
0
0
0
10
20
0
10
10
30
0
10
% A
% Cys:
20
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
10
0
10
0
20
0
10
20
% D
% Glu:
0
0
10
0
10
20
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
10
0
0
0
10
0
0
10
10
20
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
10
0
0
30
10
0
0
0
0
% I
% Lys:
30
0
0
10
30
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
20
0
0
0
0
10
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
10
10
0
0
0
0
40
10
0
20
0
0
0
0
40
% P
% Gln:
0
0
0
10
0
40
0
10
0
0
0
0
10
0
0
% Q
% Arg:
0
20
0
0
30
30
40
10
0
0
30
0
0
20
10
% R
% Ser:
10
10
20
0
0
0
0
30
30
0
10
20
30
20
0
% S
% Thr:
0
0
10
0
10
0
0
0
0
20
0
0
0
0
0
% T
% Val:
10
0
0
30
0
0
0
0
0
0
0
30
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _