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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INVS All Species: 17.88
Human Site: T77 Identified Species: 43.7
UniProt: Q9Y283 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y283 NP_055240.2 1065 117826 T77 A G A D V N K T D H S Q R T A
Chimpanzee Pan troglodytes XP_528516 1065 117759 T77 A G A D V N K T D H S Q R T A
Rhesus Macaque Macaca mulatta XP_001112073 1064 117665 T77 A G A D V N K T D H S Q R T A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O89019 1062 117110 T77 A G A D V N K T D H S R R T A
Rat Rattus norvegicus Q8VHK2 1430 150329 P111 A G S A V N V P S D E G H I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506939 1106 120372 A109 A G A D V N K A D H S Q R T A
Chicken Gallus gallus Q8UVC3 1106 122535 A77 A G A D V N R A D R S R R T A
Frog Xenopus laevis Q71S21 1002 111890 P73 H G A K V N R P D R S G R T A
Zebra Danio Brachydanio rerio Q8UVC1 1021 113016 T70 A G A G I N K T D H S Q R T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203798 1139 120682 L160 Q G A L V D K L D N D G Q T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.6 N.A. N.A. 80.5 20 N.A. 66 65.6 48.7 54.3 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 99.8 98.5 N.A. N.A. 86 31.9 N.A. 74.7 75.2 61.5 66.7 N.A. N.A. N.A. N.A. 36.9
P-Site Identity: 100 100 100 N.A. N.A. 93.3 26.6 N.A. 93.3 73.3 60 86.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 N.A. N.A. 100 33.3 N.A. 93.3 86.6 66.6 93.3 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 80 0 90 10 0 0 0 20 0 0 0 0 0 0 80 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 60 0 10 0 0 90 10 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 100 0 10 0 0 0 0 0 0 0 30 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 60 0 0 10 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 0 70 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 90 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 10 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 50 10 0 0 % Q
% Arg: 0 0 0 0 0 0 20 0 0 20 0 20 80 0 0 % R
% Ser: 0 0 10 0 0 0 0 0 10 0 80 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 0 90 0 % T
% Val: 0 0 0 0 90 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _