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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITM2B
All Species:
31.52
Human Site:
S140
Identified Species:
77.04
UniProt:
Q9Y287
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y287
NP_068839.1
266
30338
S140
P
V
P
E
F
A
D
S
D
P
A
N
I
V
H
Chimpanzee
Pan troglodytes
XP_516140
349
39546
G221
P
V
P
Q
F
G
G
G
D
P
A
D
I
I
H
Rhesus Macaque
Macaca mulatta
XP_001112854
249
28472
G121
P
V
P
Q
F
G
G
G
D
P
A
D
I
I
H
Dog
Lupus familis
XP_534119
258
29889
S132
P
V
P
E
F
A
D
S
D
P
A
N
I
V
H
Cat
Felis silvestris
Mouse
Mus musculus
O89051
266
30241
S140
P
V
P
E
F
A
D
S
D
P
A
N
I
V
H
Rat
Rattus norvegicus
Q5XIE8
266
30295
S140
P
V
P
E
F
A
D
S
D
P
A
N
I
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513545
268
30897
S140
P
V
P
E
F
A
D
S
D
P
A
N
I
V
H
Chicken
Gallus gallus
O42204
262
29991
S135
P
V
P
E
F
A
D
S
D
P
A
D
I
V
H
Frog
Xenopus laevis
NP_001080382
257
29963
S130
P
V
P
E
F
A
D
S
D
P
V
D
I
V
H
Zebra Danio
Brachydanio rerio
NP_955940
261
30494
S134
P
V
P
K
F
S
D
S
D
P
A
D
I
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.5
46.2
83.4
N.A.
95.4
96.2
N.A.
82.8
73.3
70.3
59
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.8
64.2
88.3
N.A.
98.1
98.1
N.A.
91.4
84.2
83.4
78.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
60
100
N.A.
100
100
N.A.
100
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
80
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
70
0
0
0
0
90
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
80
0
100
0
0
50
0
0
0
% D
% Glu:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
20
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
100
20
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% N
% Pro:
100
0
100
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
80
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
100
0
0
0
0
0
0
0
0
10
0
0
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _