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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASF1A All Species: 10
Human Site: T176 Identified Species: 15.71
UniProt: Q9Y294 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y294 NP_054753.1 204 22969 T176 N L Q S L L S T D A L P S A S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111289 202 22429 T165 D R L E A I E T Q D P S L G C
Dog Lupus familis XP_542021 201 22312 Q165 R L E A I E N Q D P T L G C G
Cat Felis silvestris
Mouse Mus musculus Q9CQE6 204 22924 T176 N L Q S L L S T D A L P S A S
Rat Rattus norvegicus NP_001099859 204 22882 T176 N L Q S L L S T D A L P S A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511928 201 22195 Q165 K V E N I E N Q D P A L S S G
Chicken Gallus gallus
Frog Xenopus laevis Q69DB9 201 22818 I173 H M H P V L S I E A R P S A S
Zebra Danio Brachydanio rerio Q6NY34 197 22036 P170 S E N V D P A P N A M L P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V464 218 24391 D176 H Q D E M A T D G P S T S E A
Honey Bee Apis mellifera XP_624816 198 22392 P165 S S T T N N V P E G M D A Q S
Nematode Worm Caenorhab. elegans Q17603 245 27978 L177 K V F D E D D L M P L H D D G
Sea Urchin Strong. purpuratus XP_793879 221 24848 I176 I A P T A P N I Q Q E Q S T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS09 218 24682 V176 E P F A D S V V N G E A P V F
Baker's Yeast Sacchar. cerevisiae P32447 279 31585 D176 V D D E E E E D D E E E D D D
Red Bread Mold Neurospora crassa Q7S1X9 271 30161 E176 E A D E V A D E E E Y G A D E
Conservation
Percent
Protein Identity: 100 N.A. 71.5 70.5 N.A. 99.5 98 N.A. 72 N.A. 92.6 74.5 N.A. 57.3 59.7 40.4 58.3
Protein Similarity: 100 N.A. 82.3 80.3 N.A. 99.5 99.5 N.A. 85.2 N.A. 95.5 84.8 N.A. 72.4 73 55 68.3
P-Site Identity: 100 N.A. 6.6 13.3 N.A. 100 100 N.A. 13.3 N.A. 46.6 6.6 N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 N.A. 20 40 N.A. 100 100 N.A. 53.3 N.A. 73.3 40 N.A. 33.3 40 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 48.1 37.6 38.3
Protein Similarity: N.A. N.A. N.A. 66 52.6 54.9
P-Site Identity: N.A. N.A. N.A. 0 6.6 0
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 14 14 14 7 0 0 34 7 7 14 27 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % C
% Asp: 7 7 20 7 14 7 14 14 40 7 0 7 14 20 7 % D
% Glu: 14 7 14 27 14 20 14 7 20 14 20 7 0 7 7 % E
% Phe: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 7 14 0 7 7 7 20 % G
% His: 14 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 0 0 0 14 7 0 14 0 0 0 0 0 0 0 % I
% Lys: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 27 7 0 20 27 0 7 0 0 27 20 7 0 0 % L
% Met: 0 7 0 0 7 0 0 0 7 0 14 0 0 0 0 % M
% Asn: 20 0 7 7 7 7 20 0 14 0 0 0 0 0 0 % N
% Pro: 0 7 7 7 0 14 0 14 0 27 7 27 14 7 0 % P
% Gln: 0 7 20 0 0 0 0 14 14 7 0 7 0 7 0 % Q
% Arg: 7 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % R
% Ser: 14 7 0 20 0 7 27 0 0 0 7 7 47 7 40 % S
% Thr: 0 0 7 14 0 0 7 27 0 0 7 7 0 7 7 % T
% Val: 7 14 0 7 14 0 14 7 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _