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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGL All Species: 23.64
Human Site: S24 Identified Species: 47.27
UniProt: Q9Y2B2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2B2 NP_004269.1 252 28531 S24 G F L W V W D S S E R M K S R
Chimpanzee Pan troglodytes XP_523760 250 27748 S24 G F L W V W D S S E R M K S L
Rhesus Macaque Macaca mulatta XP_001088273 256 29157 S24 G F L W V W D S S E R V K S R
Dog Lupus familis XP_536652 362 39802 S134 G F L R V W D S R E R T K S Q
Cat Felis silvestris
Mouse Mus musculus Q5SX19 252 28164 S24 G F L R V W N S A E R M R S P
Rat Rattus norvegicus O35790 252 27965 S24 G F L R V W N S A E R M R S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415845 268 29808 A19 M L L L L L L A V L R C A A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689961 325 36934 N79 T P L Y T V G N S R F C P A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996241 365 41231 Q123 G G L K Q A L Q S G I R L R S
Honey Bee Apis mellifera XP_001120540 254 29927 S12 N L I R E Y L S M Q V N E I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318312 265 30296 T28 V L F S S S S T S S S K T S F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23797 304 35427 S38 Y F T P K I V S R N N A S L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 87.8 57.7 N.A. 79.3 77.3 N.A. N.A. 54.8 N.A. 41.8 N.A. 34.5 29.9 N.A. N.A.
Protein Similarity: 100 90 92.1 62.7 N.A. 84.5 84.5 N.A. N.A. 68.2 N.A. 55.6 N.A. 45.7 45.2 N.A. N.A.
P-Site Identity: 100 93.3 93.3 73.3 N.A. 66.6 66.6 N.A. N.A. 20 N.A. 13.3 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 93.3 100 80 N.A. 86.6 86.6 N.A. N.A. 40 N.A. 40 N.A. 20 33.3 N.A. N.A.
Percent
Protein Identity: 36.9 N.A. N.A. N.A. 28.6 N.A.
Protein Similarity: 55.4 N.A. N.A. N.A. 47 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 17 0 0 9 9 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % C
% Asp: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 50 0 0 9 0 0 % E
% Phe: 0 59 9 0 0 0 0 0 0 0 9 0 0 0 9 % F
% Gly: 59 9 0 0 0 0 9 0 0 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 9 0 0 9 9 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 0 9 34 0 0 % K
% Leu: 0 25 75 9 9 9 25 0 0 9 0 0 9 9 9 % L
% Met: 9 0 0 0 0 0 0 0 9 0 0 34 0 0 0 % M
% Asn: 9 0 0 0 0 0 17 9 0 9 9 9 0 0 0 % N
% Pro: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 17 % P
% Gln: 0 0 0 0 9 0 0 9 0 9 0 0 0 0 25 % Q
% Arg: 0 0 0 34 0 0 0 0 17 9 59 9 17 9 25 % R
% Ser: 0 0 0 9 9 9 9 67 50 9 9 0 9 59 9 % S
% Thr: 9 0 9 0 9 0 0 9 0 0 0 9 9 0 0 % T
% Val: 9 0 0 0 50 9 9 0 9 0 9 9 0 0 0 % V
% Trp: 0 0 0 25 0 50 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _