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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UST All Species: 13.64
Human Site: T145 Identified Species: 37.5
UniProt: Q9Y2C2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2C2 NP_005706.1 406 47673 T145 I H N K T R L T K N E Q M E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085249 406 47650 T145 I H N K T R L T K N E Q M E L
Dog Lupus familis XP_533443 407 47761 T146 I H N K T R L T K N E Q M E L
Cat Felis silvestris
Mouse Mus musculus Q8BUB6 407 47697 T146 I H N K T R L T K N E Q M E L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q76KB1 356 41683 V128 Q V R F V K N V T S W K E M K
Frog Xenopus laevis O93336 356 41730 V128 Q V R F V K N V S S W R E M K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25722 349 41254 N126 N Q I Q F V R N V S R W H E M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17645 324 37906 H107 E R L P A F Y H G H V A F I D
Sea Urchin Strong. purpuratus XP_798108 443 50860 V184 T Y N A T R L V P E Y E K M M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 97.7 N.A. 96 N.A. N.A. N.A. 24.6 24.6 N.A. N.A. 26.6 N.A. 25.6 29.8
Protein Similarity: 100 N.A. 100 98.2 N.A. 97.7 N.A. N.A. N.A. 44.5 43.8 N.A. N.A. 46.7 N.A. 41.1 47.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 0 0 N.A. N.A. 6.6 N.A. 0 26.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 20 20 N.A. N.A. 26.6 N.A. 6.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 12 0 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 12 0 0 0 0 0 0 0 0 12 45 12 23 56 0 % E
% Phe: 0 0 0 23 12 12 0 0 0 0 0 0 12 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 0 45 0 0 0 0 0 12 0 12 0 0 12 0 0 % H
% Ile: 45 0 12 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 45 0 23 0 0 45 0 0 12 12 0 23 % K
% Leu: 0 0 12 0 0 0 56 0 0 0 0 0 0 0 45 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 45 34 23 % M
% Asn: 12 0 56 0 0 0 23 12 0 45 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % P
% Gln: 23 12 0 12 0 0 0 0 0 0 0 45 0 0 0 % Q
% Arg: 0 12 23 0 0 56 12 0 0 0 12 12 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 12 34 0 0 0 0 0 % S
% Thr: 12 0 0 0 56 0 0 45 12 0 0 0 0 0 0 % T
% Val: 0 23 0 0 23 12 0 34 12 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 23 12 0 0 0 % W
% Tyr: 0 12 0 0 0 0 12 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _