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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UST All Species: 13.64
Human Site: Y350 Identified Species: 37.5
UniProt: Q9Y2C2 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2C2 NP_005706.1 406 47673 Y350 Y E Y E F Y H Y V K E Q F H L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085249 406 47650 Y350 Y E Y E F Y H Y V K E Q F H L
Dog Lupus familis XP_533443 407 47761 Y351 Y E Y E F Y H Y V K E Q F H L
Cat Felis silvestris
Mouse Mus musculus Q8BUB6 407 47697 Y351 Y E Y E F Y H Y V R E Q F H L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q76KB1 356 41683 K298 T E K K L P T K E T I A K L Q
Frog Xenopus laevis O93336 356 41730 K298 T E K K A P S K E T T A K L Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25722 349 41254 P295 V T S S K L P P S E S T I K S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17645 324 37906 R274 Q T L S M I R R D E V Y K M E
Sea Urchin Strong. purpuratus XP_798108 443 50860 D382 D A F E G A L D I Y R N I V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 97.7 N.A. 96 N.A. N.A. N.A. 24.6 24.6 N.A. N.A. 26.6 N.A. 25.6 29.8
Protein Similarity: 100 N.A. 100 98.2 N.A. 97.7 N.A. N.A. N.A. 44.5 43.8 N.A. N.A. 46.7 N.A. 41.1 47.4
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. 6.6 6.6 N.A. N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 13.3 13.3 N.A. N.A. 6.6 N.A. 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 12 12 0 0 0 0 0 23 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % D
% Glu: 0 67 0 56 0 0 0 0 23 23 45 0 0 0 12 % E
% Phe: 0 0 12 0 45 0 0 0 0 0 0 0 45 0 0 % F
% Gly: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 45 0 0 0 0 0 0 45 0 % H
% Ile: 0 0 0 0 0 12 0 0 12 0 12 0 23 0 0 % I
% Lys: 0 0 23 23 12 0 0 23 0 34 0 0 34 12 0 % K
% Leu: 0 0 12 0 12 12 12 0 0 0 0 0 0 23 45 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 23 12 12 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 0 0 0 0 0 0 0 45 0 0 23 % Q
% Arg: 0 0 0 0 0 0 12 12 0 12 12 0 0 0 0 % R
% Ser: 0 0 12 23 0 0 12 0 12 0 12 0 0 0 23 % S
% Thr: 23 23 0 0 0 0 12 0 0 23 12 12 0 0 0 % T
% Val: 12 0 0 0 0 0 0 0 45 0 12 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 45 0 45 0 0 45 0 45 0 12 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _