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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOG
All Species:
26.36
Human Site:
S268
Identified Species:
52.73
UniProt:
Q9Y2C4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2C4
NP_001138936.1
368
41085
S268
Q
L
T
E
F
Q
V
S
L
Q
D
L
E
K
L
Chimpanzee
Pan troglodytes
XP_001171851
368
40997
S268
Q
L
T
E
F
Q
V
S
L
Q
D
L
E
K
L
Rhesus Macaque
Macaca mulatta
XP_001086498
362
40417
S268
Q
L
T
E
F
Q
V
S
L
Q
D
L
E
K
L
Dog
Lupus familis
XP_542710
368
40681
S268
Q
L
N
E
F
Q
V
S
L
Q
D
L
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C163
368
41365
S268
Q
L
S
E
F
Q
V
S
L
H
D
L
E
K
M
Rat
Rattus norvegicus
NP_001100336
368
41308
S268
Q
L
S
E
F
Q
V
S
L
H
D
L
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418536
382
43141
S282
Q
L
T
E
F
Q
V
S
I
E
D
L
E
K
M
Frog
Xenopus laevis
Q0IH72
358
40476
Q259
Q
L
P
E
Y
K
V
Q
L
E
D
L
E
K
M
Zebra Danio
Brachydanio rerio
Q502K1
343
39035
V247
H
Q
L
Q
E
F
Q
V
S
V
C
D
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95NM6
308
34492
G215
L
Y
L
P
K
L
E
G
D
G
K
K
Y
I
K
Sea Urchin
Strong. purpuratus
XP_001188021
364
40549
V262
H
T
L
K
E
Y
Q
V
S
L
D
A
L
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08466
329
37191
E236
F
F
K
L
I
V
A
E
A
P
T
A
N
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
85.8
N.A.
83.1
82
N.A.
N.A.
64.4
58.9
54.3
N.A.
N.A.
N.A.
30.1
41.8
Protein Similarity:
100
99.4
96.7
90.2
N.A.
89.4
88.3
N.A.
N.A.
79.3
74.1
72.2
N.A.
N.A.
N.A.
45.6
59.7
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
80
60
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
86.6
13.3
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
0
0
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
75
9
0
0
0
% D
% Glu:
0
0
0
67
17
0
9
9
0
17
0
0
67
17
0
% E
% Phe:
9
9
0
0
59
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% I
% Lys:
0
0
9
9
9
9
0
0
0
0
9
9
0
67
17
% K
% Leu:
9
67
25
9
0
9
0
0
59
9
0
67
17
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
9
0
0
0
9
0
% P
% Gln:
67
9
0
9
0
59
17
9
0
34
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
17
0
0
0
0
59
17
0
0
0
0
0
0
% S
% Thr:
0
9
34
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
67
17
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
9
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _