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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOG
All Species:
17.58
Human Site:
S345
Identified Species:
35.15
UniProt:
Q9Y2C4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2C4
NP_001138936.1
368
41085
S345
E
P
D
D
Y
F
M
S
R
Y
E
K
K
L
E
Chimpanzee
Pan troglodytes
XP_001171851
368
40997
S345
E
P
D
D
Y
F
M
S
R
Y
E
K
K
L
E
Rhesus Macaque
Macaca mulatta
XP_001086498
362
40417
D340
K
N
A
G
I
E
P
D
D
Y
F
M
S
R
Y
Dog
Lupus familis
XP_542710
368
40681
S345
E
P
D
D
S
F
M
S
R
Y
K
K
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C163
368
41365
S345
E
P
D
D
Y
F
L
S
R
Y
E
K
K
L
E
Rat
Rattus norvegicus
NP_001100336
368
41308
S345
E
P
D
D
Y
F
L
S
R
Y
G
K
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418536
382
43141
K359
E
P
D
E
Y
L
L
K
L
H
K
K
K
E
E
Frog
Xenopus laevis
Q0IH72
358
40476
D336
T
P
D
G
Y
L
L
D
L
Y
E
K
K
R
K
Zebra Danio
Brachydanio rerio
Q502K1
343
39035
D319
Q
E
A
G
I
A
P
D
E
H
L
K
Q
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95NM6
308
34492
I286
E
R
S
A
G
L
E
I
F
A
R
L
D
P
K
Sea Urchin
Strong. purpuratus
XP_001188021
364
40549
N339
V
P
S
D
N
L
K
N
L
Y
A
Q
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08466
329
37191
D307
N
C
Q
I
V
V
R
D
F
S
N
A
A
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
85.8
N.A.
83.1
82
N.A.
N.A.
64.4
58.9
54.3
N.A.
N.A.
N.A.
30.1
41.8
Protein Similarity:
100
99.4
96.7
90.2
N.A.
89.4
88.3
N.A.
N.A.
79.3
74.1
72.2
N.A.
N.A.
N.A.
45.6
59.7
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
86.6
N.A.
N.A.
46.6
46.6
6.6
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
93.3
N.A.
N.A.
73.3
60
33.3
N.A.
N.A.
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
9
0
0
0
9
9
9
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
59
50
0
0
0
34
9
0
0
0
9
0
0
% D
% Glu:
59
9
0
9
0
9
9
0
9
0
34
0
0
9
50
% E
% Phe:
0
0
0
0
0
42
0
0
17
0
9
0
0
0
0
% F
% Gly:
0
0
0
25
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
9
17
0
0
9
0
0
0
0
0
17
0
% I
% Lys:
9
0
0
0
0
0
9
9
0
0
17
67
67
9
25
% K
% Leu:
0
0
0
0
0
34
34
0
25
0
9
9
0
42
0
% L
% Met:
0
0
0
0
0
0
25
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
0
67
0
0
0
0
17
0
0
0
0
0
0
9
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% Q
% Arg:
0
9
0
0
0
0
9
0
42
0
9
0
0
17
9
% R
% Ser:
0
0
17
0
9
0
0
42
0
9
0
0
9
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
67
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _