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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC17A4
All Species:
19.39
Human Site:
Y251
Identified Species:
38.79
UniProt:
Q9Y2C5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2C5
NP_005486.1
497
54055
Y251
P
L
W
F
P
L
I
Y
D
D
P
V
N
H
P
Chimpanzee
Pan troglodytes
XP_527248
497
54053
Y251
L
L
W
F
P
L
I
Y
D
D
P
V
N
H
P
Rhesus Macaque
Macaca mulatta
XP_001082785
497
54256
Y251
L
L
W
F
P
L
I
Y
D
D
P
V
N
H
P
Dog
Lupus familis
XP_545377
526
57357
Y280
L
L
W
F
T
V
I
Y
D
D
P
M
H
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCM1
492
53649
Y246
L
L
W
F
P
L
V
Y
D
D
P
Q
N
H
P
Rat
Rattus norvegicus
Q62795
465
51332
E232
H
P
Y
M
S
S
S
E
K
D
Y
I
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519993
502
53998
Y253
I
F
W
F
F
L
V
Y
K
D
P
Q
S
H
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC8
576
63887
A261
L
V
S
Y
E
S
P
A
Q
H
P
T
I
S
E
Zebra Danio
Brachydanio rerio
Q1L8X9
590
64796
A274
L
L
A
Y
N
S
P
A
V
H
P
T
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7S5
529
58354
H253
I
A
F
L
I
F
V
H
E
D
P
S
S
H
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34644
576
63090
K264
W
F
C
V
T
F
E
K
P
A
F
H
P
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX78
541
59595
F292
K
F
G
W
P
S
V
F
Y
S
F
G
S
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.3
53.9
N.A.
78.2
44
N.A.
47.6
N.A.
26.9
27.4
N.A.
29.8
N.A.
24.8
N.A.
Protein Similarity:
100
99.8
98.9
69.9
N.A.
88.1
62.3
N.A.
62.7
N.A.
41.8
44.4
N.A.
50.8
N.A.
42.5
N.A.
P-Site Identity:
100
93.3
93.3
66.6
N.A.
80
6.6
N.A.
53.3
N.A.
6.6
13.3
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
86.6
20
N.A.
66.6
N.A.
20
20
N.A.
60
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
17
0
9
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
42
67
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
9
9
0
0
0
0
0
17
% E
% Phe:
0
25
9
50
9
17
0
9
0
0
17
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% G
% His:
9
0
0
0
0
0
0
9
0
17
0
9
9
59
0
% H
% Ile:
17
0
0
0
9
0
34
0
0
0
0
9
17
0
9
% I
% Lys:
9
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% K
% Leu:
50
50
0
9
0
42
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
34
0
0
% N
% Pro:
9
9
0
0
42
0
17
0
9
0
75
0
9
0
59
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
9
34
9
0
0
9
0
9
25
25
9
% S
% Thr:
0
0
0
0
17
0
0
0
0
0
0
17
9
9
0
% T
% Val:
0
9
0
9
0
9
34
0
9
0
0
25
0
0
0
% V
% Trp:
9
0
50
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
17
0
0
0
50
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _