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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR6
All Species:
16.67
Human Site:
S649
Identified Species:
52.38
UniProt:
Q9Y2C9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2C9
NP_006059.2
796
91880
S649
F
H
A
F
I
S
Y
S
E
H
D
S
A
W
V
Chimpanzee
Pan troglodytes
B3Y613
784
89806
V645
N
I
C
Y
D
A
F
V
S
Y
S
E
R
D
A
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
V645
D
I
C
Y
D
A
F
V
S
Y
S
E
R
D
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPW9
795
91098
S649
F
H
A
F
V
S
Y
S
E
H
D
S
A
W
V
Rat
Rattus norvegicus
NP_997487
806
92548
S660
F
H
A
F
V
S
Y
S
E
H
D
S
A
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512973
790
88926
S644
F
H
V
F
V
S
Y
S
E
R
D
A
T
W
V
Chicken
Gallus gallus
Q9DD78
793
90748
F653
K
D
I
C
Y
D
A
F
V
S
Y
S
E
N
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124065
795
91076
S649
F
H
A
F
V
S
Y
S
Q
K
N
A
G
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.6
29.7
N.A.
N.A.
73.8
73.4
N.A.
53.2
29
N.A.
35
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.3
51.2
N.A.
N.A.
86
84.4
N.A.
70.9
51.1
N.A.
56.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
93.3
93.3
N.A.
66.6
6.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
N.A.
N.A.
100
100
N.A.
80
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
25
13
0
0
0
0
25
38
0
25
% A
% Cys:
0
0
25
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
0
25
13
0
0
0
0
50
0
0
25
13
% D
% Glu:
0
0
0
0
0
0
0
0
50
0
0
25
13
0
0
% E
% Phe:
63
0
0
63
0
0
25
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
0
63
0
0
0
0
0
0
0
38
0
0
0
0
0
% H
% Ile:
0
25
13
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
25
0
0
% R
% Ser:
0
0
0
0
0
63
0
63
25
13
25
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
13
0
50
0
0
25
13
0
0
0
0
0
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% W
% Tyr:
0
0
0
25
13
0
63
0
0
25
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _