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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA5B
All Species:
20.91
Human Site:
S74
Identified Species:
46
UniProt:
Q9Y2D0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D0
NP_009151.1
317
36434
S74
I
N
I
R
W
R
D
S
V
Y
D
P
G
L
K
Chimpanzee
Pan troglodytes
Q7M317
261
28893
V69
N
V
G
H
S
F
H
V
N
F
E
D
N
D
N
Rhesus Macaque
Macaca mulatta
P00916
261
28918
V69
N
V
G
H
S
F
H
V
N
F
E
D
N
D
N
Dog
Lupus familis
XP_543579
317
36502
S74
I
N
I
R
W
R
D
S
V
F
D
P
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZA0
317
36604
S74
I
N
I
R
W
R
D
S
V
Y
D
P
G
L
K
Rat
Rattus norvegicus
Q66HG6
317
36579
S74
I
N
I
R
W
R
D
S
V
Y
D
P
G
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515632
315
36403
S72
I
N
I
Q
W
R
D
S
V
Y
D
P
C
L
K
Chicken
Gallus gallus
P07630
260
28989
V68
N
N
G
H
S
F
N
V
E
F
D
D
S
S
D
Frog
Xenopus laevis
NP_001084659
318
36672
S76
I
N
I
R
I
R
D
S
V
F
H
P
Q
L
A
Zebra Danio
Brachydanio rerio
Q92051
260
28659
V68
N
N
G
H
S
F
Q
V
D
F
V
D
D
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27504
246
28103
D55
Y
D
H
P
I
Q
G
D
I
V
N
N
G
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.6
40
92.4
N.A.
89.2
88.6
N.A.
79.8
42.2
61.6
42.9
N.A.
N.A.
N.A.
31.8
N.A.
Protein Similarity:
100
57.4
57.7
96.2
N.A.
93.6
94.6
N.A.
88.3
55.5
74.2
56.1
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
100
0
0
86.6
N.A.
100
100
N.A.
86.6
13.3
66.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
100
100
N.A.
93.3
26.6
73.3
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
0
0
0
55
10
10
0
55
37
10
28
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
19
0
0
0
0
% E
% Phe:
0
0
0
0
0
37
0
0
0
55
0
0
0
0
0
% F
% Gly:
0
0
37
0
0
0
10
0
0
0
0
0
37
0
0
% G
% His:
0
0
10
37
0
0
19
0
0
0
10
0
0
10
0
% H
% Ile:
55
0
55
0
19
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
37
73
0
0
0
0
10
0
19
0
10
10
19
0
28
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
55
0
0
0
% P
% Gln:
0
0
0
10
0
10
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
46
0
55
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
37
0
0
55
0
0
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
19
0
0
0
0
0
37
55
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
37
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _