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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6B
All Species:
31.21
Human Site:
S198
Identified Species:
57.22
UniProt:
Q9Y2D4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D4
NP_056004.1
672
78234
S198
R
E
E
I
K
D
V
S
M
S
D
L
K
D
F
Chimpanzee
Pan troglodytes
XP_515544
1040
118952
S427
R
E
E
I
K
D
V
S
M
S
D
L
K
D
F
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
S317
R
E
D
I
K
E
I
S
M
S
D
L
K
D
F
Dog
Lupus familis
XP_540235
811
94186
S198
R
E
E
I
K
D
V
S
M
S
D
L
K
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
C194
R
E
D
M
M
N
Y
C
M
S
D
L
T
Y
G
Rat
Rattus norvegicus
O54923
804
93159
S196
R
E
D
I
K
D
I
S
M
S
D
L
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
S491
R
E
E
I
K
D
I
S
M
S
D
L
K
D
F
Chicken
Gallus gallus
XP_420892
799
92606
S186
R
E
E
I
K
E
V
S
M
S
D
L
K
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
K176
Q
I
Q
I
P
I
I
K
E
N
I
R
R
S
S
Honey Bee
Apis mellifera
XP_393572
765
88660
Q170
R
F
S
S
Q
I
T
Q
Q
I
P
Q
L
R
E
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
A212
R
L
E
I
K
E
K
A
Y
S
E
F
K
D
F
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
S190
R
Q
N
I
K
E
A
S
M
S
D
L
K
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.2
51.5
82
N.A.
57.1
58
N.A.
43.2
72.4
N.A.
20.2
N.A.
38.2
46
31.8
52.9
Protein Similarity:
100
64.6
61.2
82.4
N.A.
68.8
69.6
N.A.
51.5
76.7
N.A.
33.9
N.A.
56.2
61.8
51
69
P-Site Identity:
100
100
80
100
N.A.
40
86.6
N.A.
93.3
93.3
N.A.
0
N.A.
6.6
6.6
53.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
60
100
N.A.
100
100
N.A.
0
N.A.
40
13.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
0
0
39
0
0
0
0
70
0
0
70
0
% D
% Glu:
0
62
47
0
0
31
0
0
8
0
8
0
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
70
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
77
0
16
31
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
70
0
8
8
0
0
0
0
70
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
70
8
0
0
% L
% Met:
0
0
0
8
8
0
0
0
70
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
8
8
0
8
0
0
8
8
0
0
8
0
0
0
% Q
% Arg:
85
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% R
% Ser:
0
0
8
8
0
0
0
62
0
77
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _