KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6B
All Species:
12.42
Human Site:
S246
Identified Species:
22.78
UniProt:
Q9Y2D4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D4
NP_056004.1
672
78234
S246
R
I
G
S
K
R
K
S
K
K
D
A
Y
I
I
Chimpanzee
Pan troglodytes
XP_515544
1040
118952
S475
R
I
G
S
K
R
K
S
K
K
D
A
Y
I
I
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
F361
Q
K
Q
N
K
M
K
F
G
K
N
M
Y
I
N
Dog
Lupus familis
XP_540235
811
94186
S246
R
I
G
S
K
R
K
S
K
K
D
V
Y
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
F238
Q
K
Q
N
N
M
R
F
G
K
N
M
H
V
N
Rat
Rattus norvegicus
O54923
804
93159
F240
Q
K
Q
T
N
M
R
F
G
K
N
M
H
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
S538
T
N
I
T
C
G
R
S
L
Y
A
K
N
R
I
Chicken
Gallus gallus
XP_420892
799
92606
S234
R
I
S
G
G
K
K
S
K
K
E
A
C
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
D216
T
K
Q
L
Q
K
R
D
I
N
A
I
I
A
E
Honey Bee
Apis mellifera
XP_393572
765
88660
K210
E
V
A
M
R
H
V
K
Q
L
T
V
E
A
E
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
A259
A
K
K
I
Q
E
E
A
R
K
N
A
S
N
V
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
A230
E
T
S
A
F
S
R
A
R
H
R
T
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.2
51.5
82
N.A.
57.1
58
N.A.
43.2
72.4
N.A.
20.2
N.A.
38.2
46
31.8
52.9
Protein Similarity:
100
64.6
61.2
82.4
N.A.
68.8
69.6
N.A.
51.5
76.7
N.A.
33.9
N.A.
56.2
61.8
51
69
P-Site Identity:
100
100
33.3
86.6
N.A.
6.6
6.6
N.A.
13.3
46.6
N.A.
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
53.3
86.6
N.A.
46.6
46.6
N.A.
26.6
60
N.A.
0
N.A.
20
20
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
16
0
0
16
31
0
24
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
24
0
0
0
0
% D
% Glu:
16
0
0
0
0
8
8
0
0
0
8
0
8
0
16
% E
% Phe:
0
0
0
0
8
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
8
8
8
0
0
24
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
16
0
0
% H
% Ile:
0
31
8
8
0
0
0
0
8
0
0
8
8
24
31
% I
% Lys:
0
39
8
0
31
16
39
8
31
62
0
8
0
8
0
% K
% Leu:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
24
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
8
0
16
16
0
0
0
0
8
31
0
8
8
24
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
0
31
0
16
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
31
0
0
0
8
24
39
0
16
0
8
0
0
8
0
% R
% Ser:
0
0
16
24
0
8
0
39
0
0
0
0
8
0
0
% S
% Thr:
16
8
0
16
0
0
0
0
0
0
8
8
0
8
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
16
8
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _