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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6B
All Species:
22.12
Human Site:
S262
Identified Species:
40.56
UniProt:
Q9Y2D4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D4
NP_056004.1
672
78234
S262
D
T
E
I
E
S
T
S
P
K
S
E
Q
D
S
Chimpanzee
Pan troglodytes
XP_515544
1040
118952
S491
D
T
E
I
E
S
T
S
P
K
S
E
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
N377
D
R
I
P
E
E
R
N
E
T
V
L
K
H
S
Dog
Lupus familis
XP_540235
811
94186
S262
D
T
E
L
E
S
T
S
P
K
S
E
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
S254
D
R
I
L
E
E
K
S
D
V
I
P
K
H
A
Rat
Rattus norvegicus
O54923
804
93159
S256
D
R
T
L
E
E
K
S
D
I
I
L
K
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
S554
D
E
G
K
E
V
P
S
K
Q
T
L
E
E
E
Chicken
Gallus gallus
XP_420892
799
92606
S250
D
L
E
V
K
N
T
S
P
M
S
E
Q
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
S8
M
A
S
A
S
T
S
S
S
N
E
S
E
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
E232
M
Q
Q
M
N
G
G
E
A
G
G
A
G
A
G
Honey Bee
Apis mellifera
XP_393572
765
88660
S226
I
G
R
K
K
K
R
S
H
V
T
N
S
N
E
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
S275
I
E
V
S
A
D
G
S
I
V
K
K
N
M
S
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
K246
S
P
L
T
E
A
D
K
D
S
V
G
D
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.2
51.5
82
N.A.
57.1
58
N.A.
43.2
72.4
N.A.
20.2
N.A.
38.2
46
31.8
52.9
Protein Similarity:
100
64.6
61.2
82.4
N.A.
68.8
69.6
N.A.
51.5
76.7
N.A.
33.9
N.A.
56.2
61.8
51
69
P-Site Identity:
100
100
20
93.3
N.A.
20
20
N.A.
20
66.6
N.A.
6.6
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
40
40
N.A.
46.6
86.6
N.A.
26.6
N.A.
13.3
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
8
0
0
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
0
0
8
8
0
24
0
0
0
8
31
0
% D
% Glu:
0
16
31
0
62
24
0
8
8
0
8
31
16
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
0
0
8
16
0
0
8
8
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
24
0
% H
% Ile:
16
0
16
16
0
0
0
0
8
8
16
0
0
0
0
% I
% Lys:
0
0
0
16
16
8
16
8
8
24
8
8
24
0
0
% K
% Leu:
0
8
8
24
0
0
0
0
0
0
0
24
0
0
0
% L
% Met:
16
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
0
0
0
0
8
8
0
8
0
8
0
8
8
8
0
% N
% Pro:
0
8
0
8
0
0
8
0
31
0
0
8
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
8
0
0
31
0
8
% Q
% Arg:
0
24
8
0
0
0
16
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
8
8
24
8
77
8
8
31
8
8
8
47
% S
% Thr:
0
24
8
8
0
8
31
0
0
8
16
0
0
0
8
% T
% Val:
0
0
8
8
0
8
0
0
0
24
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _