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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6B
All Species:
18.79
Human Site:
S269
Identified Species:
34.44
UniProt:
Q9Y2D4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D4
NP_056004.1
672
78234
S269
S
P
K
S
E
Q
D
S
G
I
L
D
V
E
D
Chimpanzee
Pan troglodytes
XP_515544
1040
118952
S498
S
P
K
S
E
Q
D
S
G
I
L
D
V
E
D
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
S384
N
E
T
V
L
K
H
S
L
E
E
E
D
E
N
Dog
Lupus familis
XP_540235
811
94186
S269
S
P
K
S
E
Q
D
S
G
I
L
D
V
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
A261
S
D
V
I
P
K
H
A
L
E
E
E
A
E
N
Rat
Rattus norvegicus
O54923
804
93159
T263
S
D
I
I
L
K
H
T
L
E
E
E
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
E561
S
K
Q
T
L
E
E
E
D
D
N
E
E
E
V
Chicken
Gallus gallus
XP_420892
799
92606
S257
S
P
M
S
E
Q
D
S
G
I
L
D
V
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
Q15
S
S
N
E
S
E
S
Q
S
V
L
T
W
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
G239
E
A
G
G
A
G
A
G
G
D
D
D
G
A
N
Honey Bee
Apis mellifera
XP_393572
765
88660
E233
S
H
V
T
N
S
N
E
S
E
E
E
L
S
A
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
S282
S
I
V
K
K
N
M
S
P
K
R
N
M
K
M
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
M253
K
D
S
V
G
D
F
M
F
E
E
E
E
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.2
51.5
82
N.A.
57.1
58
N.A.
43.2
72.4
N.A.
20.2
N.A.
38.2
46
31.8
52.9
Protein Similarity:
100
64.6
61.2
82.4
N.A.
68.8
69.6
N.A.
51.5
76.7
N.A.
33.9
N.A.
56.2
61.8
51
69
P-Site Identity:
100
100
13.3
100
N.A.
13.3
13.3
N.A.
13.3
93.3
N.A.
20
N.A.
13.3
6.6
13.3
6.6
P-Site Similarity:
100
100
40
100
N.A.
40
40
N.A.
46.6
93.3
N.A.
33.3
N.A.
20
33.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
8
0
0
0
0
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
0
8
31
0
8
16
8
39
8
0
31
% D
% Glu:
8
8
0
8
31
16
8
16
0
39
39
47
16
77
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
8
0
8
39
0
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
24
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
16
0
0
0
0
0
31
0
0
0
0
0
% I
% Lys:
8
8
24
8
8
24
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
24
0
0
0
24
0
39
0
8
0
0
% L
% Met:
0
0
8
0
0
0
8
8
0
0
0
0
8
0
8
% M
% Asn:
8
0
8
0
8
8
8
0
0
0
8
8
0
0
31
% N
% Pro:
0
31
0
0
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
31
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
77
8
8
31
8
8
8
47
16
0
0
0
0
8
0
% S
% Thr:
0
0
8
16
0
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
0
24
16
0
0
0
0
0
8
0
0
31
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _