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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6B
All Species:
32.12
Human Site:
Y611
Identified Species:
58.89
UniProt:
Q9Y2D4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D4
NP_056004.1
672
78234
Y611
H
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
Chimpanzee
Pan troglodytes
XP_515544
1040
118952
Y840
H
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
Y723
H
A
A
E
G
E
I
Y
T
K
L
N
Q
K
I
Dog
Lupus familis
XP_540235
811
94186
Y611
H
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
Y600
H
A
A
E
G
E
I
Y
T
K
L
N
Q
K
I
Rat
Rattus norvegicus
O54923
804
93159
Y602
H
A
A
E
G
E
I
Y
T
K
L
N
Q
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
Y896
H
S
A
E
G
E
I
Y
M
K
L
N
Q
K
I
Chicken
Gallus gallus
XP_420892
799
92606
Y599
H
A
A
E
E
E
I
Y
T
N
L
N
Q
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
R328
C
L
M
G
H
E
R
R
Q
T
L
N
L
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
C574
K
Q
V
G
L
R
I
C
S
K
I
D
E
F
F
Honey Bee
Apis mellifera
XP_393572
765
88660
C565
D
D
A
E
K
Q
I
C
E
K
L
K
N
K
L
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
D623
S
E
V
E
Q
Q
I
D
E
C
M
R
S
K
V
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
Y587
S
E
A
E
L
E
I
Y
R
R
L
N
E
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.2
51.5
82
N.A.
57.1
58
N.A.
43.2
72.4
N.A.
20.2
N.A.
38.2
46
31.8
52.9
Protein Similarity:
100
64.6
61.2
82.4
N.A.
68.8
69.6
N.A.
51.5
76.7
N.A.
33.9
N.A.
56.2
61.8
51
69
P-Site Identity:
100
100
86.6
100
N.A.
86.6
86.6
N.A.
73.3
100
N.A.
20
N.A.
6.6
33.3
20
53.3
P-Site Similarity:
100
100
86.6
100
N.A.
86.6
86.6
N.A.
80
100
N.A.
20
N.A.
33.3
53.3
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
77
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
16
0
85
31
77
0
0
16
0
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
16
31
0
0
0
0
0
0
0
0
0
0
% G
% His:
62
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
93
0
0
0
8
0
0
8
62
% I
% Lys:
8
0
0
0
8
0
0
0
0
47
0
8
0
85
0
% K
% Leu:
0
8
0
0
16
0
0
0
0
0
85
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
31
0
77
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
16
0
0
8
0
0
0
62
0
0
% Q
% Arg:
0
0
0
0
0
8
8
8
8
8
0
8
0
0
0
% R
% Ser:
16
8
0
0
0
0
0
0
8
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
54
8
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _