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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP2
All Species:
26.97
Human Site:
T249
Identified Species:
65.93
UniProt:
Q9Y2D5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2D5
NP_001004065.2
859
94661
T249
W
N
P
P
Q
E
K
T
I
E
E
Q
L
D
E
Chimpanzee
Pan troglodytes
XP_001146667
679
75234
K122
D
G
E
D
E
E
M
K
T
Y
R
L
D
A
G
Rhesus Macaque
Macaca mulatta
XP_001106950
1106
122362
T480
W
N
P
P
Q
E
K
T
I
E
E
Q
L
D
E
Dog
Lupus familis
XP_855215
435
47166
Cat
Felis silvestris
Mouse
Mus musculus
O54931
893
98560
T249
W
N
P
P
Q
E
K
T
I
E
E
Q
L
D
E
Rat
Rattus norvegicus
Q5U301
870
95922
T249
W
N
P
P
Q
K
K
T
I
E
E
Q
L
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512747
1312
145328
T692
W
N
P
P
Q
E
K
T
L
E
E
Q
L
D
E
Chicken
Gallus gallus
XP_424909
1249
138678
T634
W
N
P
P
Q
E
K
T
L
E
E
Q
L
D
E
Frog
Xenopus laevis
NP_001088387
848
94887
T246
W
N
P
P
Q
E
K
T
I
E
E
Q
L
D
S
Zebra Danio
Brachydanio rerio
XP_001342301
817
91293
Q240
A
K
W
W
N
P
P
Q
E
K
T
L
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
75.6
23.1
N.A.
81.9
84.5
N.A.
47.8
44.4
49.9
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
34.3
76.4
32.9
N.A.
86.6
88.8
N.A.
53.8
51.7
65.4
57.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
100
93.3
N.A.
93.3
93.3
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
0
N.A.
100
100
N.A.
100
100
93.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
0
10
70
0
% D
% Glu:
0
0
10
0
10
70
0
0
10
70
70
0
10
10
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
70
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
20
0
0
20
70
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
70
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
70
0
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
70
0
0
10
0
0
0
70
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
70
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
70
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _