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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIP2C
All Species:
18.79
Human Site:
S251
Identified Species:
41.33
UniProt:
Q9Y2E4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2E4
NP_055789.1
1556
170767
S251
T
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Chimpanzee
Pan troglodytes
XP_507617
1605
176261
S299
T
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Rhesus Macaque
Macaca mulatta
XP_001082866
1575
170969
D262
S
N
R
S
S
L
M
D
T
A
D
G
V
P
V
Dog
Lupus familis
XP_853218
1686
182523
S244
T
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWT5
1523
165255
D247
L
K
E
F
F
V
D
D
F
E
E
L
L
E
V
Rat
Rattus norvegicus
NP_001100830
1612
176871
S307
T
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509877
1556
170889
S251
T
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Chicken
Gallus gallus
XP_418558
1607
176339
S303
G
D
G
V
P
V
S
S
R
V
S
A
K
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NVJ5
1577
171660
G255
A
V
K
G
I
S
R
G
Q
S
R
S
S
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0S9
1773
194136
N372
N
V
S
Q
N
E
L
N
E
T
D
A
N
G
K
Honey Bee
Apis mellifera
XP_391894
1679
181987
P357
L
K
R
P
K
R
R
P
L
P
E
F
Y
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
72.3
85.2
N.A.
75.2
95.8
N.A.
98.7
92.7
N.A.
71
N.A.
52.7
57.8
N.A.
N.A.
Protein Similarity:
100
94.7
84
87.4
N.A.
85.6
96
N.A.
99.2
94.7
N.A.
84.5
N.A.
66.8
71.5
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
0
100
N.A.
100
6.6
N.A.
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
20
100
N.A.
100
13.3
N.A.
33.3
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
10
0
19
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
46
0
0
0
10
19
0
0
19
0
0
0
10
% D
% Glu:
0
0
10
0
0
10
0
0
10
10
19
0
0
19
0
% E
% Phe:
0
0
0
10
10
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
10
46
10
55
0
0
0
10
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
46
% I
% Lys:
0
19
10
0
10
0
0
0
0
0
0
0
10
46
10
% K
% Leu:
19
0
0
0
0
10
10
0
10
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% M
% Asn:
10
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
10
46
0
10
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
19
0
0
10
19
0
10
46
10
0
0
0
0
% R
% Ser:
10
0
10
10
10
10
10
55
46
10
10
55
10
0
0
% S
% Thr:
46
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% T
% Val:
0
19
0
10
46
19
46
0
0
10
46
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _