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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTX4
All Species:
22.12
Human Site:
S491
Identified Species:
44.24
UniProt:
Q9Y2E6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2E6
NP_055992.1
619
67258
S491
E
Y
H
L
I
P
H
S
L
P
G
H
P
D
C
Chimpanzee
Pan troglodytes
XP_508449
856
91120
S728
E
Y
H
L
I
P
H
S
L
P
G
H
P
D
C
Rhesus Macaque
Macaca mulatta
XP_001088765
736
78221
S608
E
Y
H
L
I
P
H
S
L
P
G
H
P
D
C
Dog
Lupus familis
XP_540579
904
95256
S776
E
Y
H
L
I
P
H
S
L
P
G
H
P
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDK8
616
66802
S488
E
Y
H
L
I
P
H
S
L
P
G
H
P
D
C
Rat
Rattus norvegicus
NP_001041320
321
35066
R204
H
P
D
C
K
T
I
R
I
I
Y
S
I
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506388
341
37115
I223
G
H
P
D
C
K
T
I
R
I
I
Y
N
I
P
Chicken
Gallus gallus
XP_423367
267
29365
R150
H
S
D
C
K
T
I
R
I
I
Y
N
I
P
P
Frog
Xenopus laevis
Q8AW93
623
68315
P495
K
M
E
F
H
V
I
P
H
S
L
P
G
F
S
Zebra Danio
Brachydanio rerio
XP_002663104
524
57426
K407
L
P
G
H
S
D
I
K
T
I
R
I
V
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23985
738
82168
G601
F
I
E
C
P
V
C
G
I
V
Y
G
E
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184641
693
75218
S567
D
Y
H
V
I
P
H
S
L
P
G
F
P
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72
82.6
59.9
N.A.
93.8
50
N.A.
51.8
39
61.4
53.3
N.A.
27.7
N.A.
N.A.
38.6
Protein Similarity:
100
72
83.5
62.5
N.A.
95.8
51.8
N.A.
53.7
41.8
73.8
67.3
N.A.
42.8
N.A.
N.A.
55.5
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
13.3
6.6
0
N.A.
6.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
25
9
0
9
0
0
0
0
0
0
0
50
% C
% Asp:
9
0
17
9
0
9
0
0
0
0
0
0
0
42
9
% D
% Glu:
42
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
9
0
9
0
0
0
0
9
0
0
50
9
9
0
0
% G
% His:
17
9
50
9
9
0
50
0
9
0
0
42
0
0
0
% H
% Ile:
0
9
0
0
50
0
34
9
25
34
9
9
17
9
0
% I
% Lys:
9
0
0
0
17
9
0
9
0
0
0
0
0
9
0
% K
% Leu:
9
0
0
42
0
0
0
0
50
0
9
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% N
% Pro:
0
17
9
0
9
50
0
9
0
50
0
9
50
17
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
9
0
9
0
0
0
0
% R
% Ser:
0
9
0
0
9
0
0
50
0
9
0
9
0
9
9
% S
% Thr:
0
0
0
0
0
17
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
17
0
0
0
9
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
0
0
0
0
25
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _