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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTX4 All Species: 13.64
Human Site: T112 Identified Species: 27.27
UniProt: Q9Y2E6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2E6 NP_055992.1 619 67258 T112 Y D M E V G I T I Q H A Y E K
Chimpanzee Pan troglodytes XP_508449 856 91120 T349 Y D M E V G I T I Q H A Y E K
Rhesus Macaque Macaca mulatta XP_001088765 736 78221 T229 Y D M E V G I T I Q H A Y E K
Dog Lupus familis XP_540579 904 95256 L300 P E G V R C A L V W E R Q A P
Cat Felis silvestris
Mouse Mus musculus Q6PDK8 616 66802 T112 Y D M E V G I T I Q Y A Y E K
Rat Rattus norvegicus NP_001041320 321 35066
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506388 341 37115
Chicken Gallus gallus XP_423367 267 29365
Frog Xenopus laevis Q8AW93 623 68315 W117 W E N D A G S W T P Y D T E I
Zebra Danio Brachydanio rerio XP_002663104 524 57426 W30 W E N D C G S W T P Y D M E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23985 738 82168 E158 M H V Q C I I E D A W A R G E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184641 693 75218 G189 V L E V D P G G C A D A S I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72 82.6 59.9 N.A. 93.8 50 N.A. 51.8 39 61.4 53.3 N.A. 27.7 N.A. N.A. 38.6
Protein Similarity: 100 72 83.5 62.5 N.A. 95.8 51.8 N.A. 53.7 41.8 73.8 67.3 N.A. 42.8 N.A. N.A. 55.5
P-Site Identity: 100 100 100 0 N.A. 93.3 0 N.A. 0 0 13.3 13.3 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 0 N.A. 0 0 40 40 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 0 17 0 50 0 9 0 % A
% Cys: 0 0 0 0 17 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 34 0 17 9 0 0 0 9 0 9 17 0 0 0 % D
% Glu: 0 25 9 34 0 0 0 9 0 0 9 0 0 50 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 50 9 9 0 0 0 0 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 25 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 42 0 34 0 0 0 0 9 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42 % K
% Leu: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % L
% Met: 9 0 34 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 9 0 0 0 17 0 0 0 0 9 % P
% Gln: 0 0 0 9 0 0 0 0 0 34 0 0 9 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 9 9 0 0 % R
% Ser: 0 0 0 0 0 0 17 0 0 0 0 0 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 34 17 0 0 0 9 0 0 % T
% Val: 9 0 9 17 34 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 17 0 0 0 0 0 0 17 0 9 9 0 0 0 0 % W
% Tyr: 34 0 0 0 0 0 0 0 0 0 25 0 34 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _