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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTX4 All Species: 19.09
Human Site: T245 Identified Species: 38.18
UniProt: Q9Y2E6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2E6 NP_055992.1 619 67258 T245 K P L D S T G T I R G P L K T
Chimpanzee Pan troglodytes XP_508449 856 91120 T482 K P L D S T G T I R G P L K T
Rhesus Macaque Macaca mulatta XP_001088765 736 78221 T362 K P L D S T G T I R G P V K T
Dog Lupus familis XP_540579 904 95256 T530 K S P D G L G T I R A P V R T
Cat Felis silvestris
Mouse Mus musculus Q6PDK8 616 66802 T242 K P L D T T G T I R G P G K T
Rat Rattus norvegicus NP_001041320 321 35066
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506388 341 37115
Chicken Gallus gallus XP_423367 267 29365
Frog Xenopus laevis Q8AW93 623 68315 S249 H P S G L R Q S N T Y S G G A
Zebra Danio Brachydanio rerio XP_002663104 524 57426 G161 R Q S N T F A G S S L W S P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23985 738 82168 S355 S S S S S S A S L H H A N H L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184641 693 75218 T321 T S S A G S S T G S T G R S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72 82.6 59.9 N.A. 93.8 50 N.A. 51.8 39 61.4 53.3 N.A. 27.7 N.A. N.A. 38.6
Protein Similarity: 100 72 83.5 62.5 N.A. 95.8 51.8 N.A. 53.7 41.8 73.8 67.3 N.A. 42.8 N.A. N.A. 55.5
P-Site Identity: 100 100 93.3 53.3 N.A. 86.6 0 N.A. 0 0 6.6 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 66.6 N.A. 93.3 0 N.A. 0 0 13.3 26.6 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 17 0 0 0 9 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 17 0 42 9 9 0 34 9 17 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % I
% Lys: 42 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % K
% Leu: 0 0 34 0 9 9 0 0 9 0 9 0 17 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % N
% Pro: 0 42 9 0 0 0 0 0 0 0 0 42 0 9 0 % P
% Gln: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 42 0 0 9 9 0 % R
% Ser: 9 25 34 9 34 17 9 17 9 17 0 9 9 9 9 % S
% Thr: 9 0 0 0 17 34 0 50 0 9 9 0 0 0 50 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _