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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTX4 All Species: 21.82
Human Site: T500 Identified Species: 43.64
UniProt: Q9Y2E6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2E6 NP_055992.1 619 67258 T500 P G H P D C K T I R I I Y S I
Chimpanzee Pan troglodytes XP_508449 856 91120 T737 P G H P D C K T I R I I Y S I
Rhesus Macaque Macaca mulatta XP_001088765 736 78221 T617 P G H P D C K T I R I I Y S I
Dog Lupus familis XP_540579 904 95256 T785 P G H P D C K T I R I I Y S I
Cat Felis silvestris
Mouse Mus musculus Q6PDK8 616 66802 T497 P G H P D C K T I R I I Y S I
Rat Rattus norvegicus NP_001041320 321 35066 I213 I Y S I P P G I Q G P E H P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506388 341 37115 G232 I I Y N I P P G I Q G P E H P
Chicken Gallus gallus XP_423367 267 29365 V159 I Y N I P P G V Q G P E H P N
Frog Xenopus laevis Q8AW93 623 68315 C504 S L P G F S D C K T I R I V Y
Zebra Danio Brachydanio rerio XP_002663104 524 57426 P416 I R I V Y D I P A G V Q T T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23985 738 82168 N610 V Y G E K V G N Q P I G S M S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184641 693 75218 T576 P G F P S C G T I R I I Y N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72 82.6 59.9 N.A. 93.8 50 N.A. 51.8 39 61.4 53.3 N.A. 27.7 N.A. N.A. 38.6
Protein Similarity: 100 72 83.5 62.5 N.A. 95.8 51.8 N.A. 53.7 41.8 73.8 67.3 N.A. 42.8 N.A. N.A. 55.5
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 0 6.6 0 N.A. 6.6 N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 20 13.3 6.6 13.3 N.A. 6.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 50 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 42 9 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 17 9 0 9 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 9 9 0 0 34 9 0 25 9 9 0 0 0 % G
% His: 0 0 42 0 0 0 0 0 0 0 0 0 17 9 0 % H
% Ile: 34 9 9 17 9 0 9 9 59 0 67 50 9 0 50 % I
% Lys: 0 0 0 0 9 0 42 0 9 0 0 0 0 0 0 % K
% Leu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 9 9 0 0 0 9 0 0 0 0 0 9 17 % N
% Pro: 50 0 9 50 17 25 9 9 0 9 17 9 0 17 9 % P
% Gln: 0 0 0 0 0 0 0 0 25 9 0 9 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 50 0 9 0 0 0 % R
% Ser: 9 0 9 0 9 9 0 0 0 0 0 0 9 42 9 % S
% Thr: 0 0 0 0 0 0 0 50 0 9 0 0 9 9 0 % T
% Val: 9 0 0 9 0 9 0 9 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 25 9 0 9 0 0 0 0 0 0 0 50 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _