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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A8 All Species: 35.76
Human Site: S492 Identified Species: 65.56
UniProt: Q9Y2E8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2E8 NP_056081.1 581 65422 S492 N K K D V N L S K T E K M G N
Chimpanzee Pan troglodytes XP_514716 751 84176 S662 N K K D V N L S K T E K M G N
Rhesus Macaque Macaca mulatta XP_001103158 318 36448 F231 M A V G P P F F P A Q G N T V
Dog Lupus familis XP_854123 580 65250 S491 N K K D V N L S K T E K M G N
Cat Felis silvestris
Mouse Mus musculus Q8R4D1 576 64718 S487 S K K D V N L S K T E K M G N
Rat Rattus norvegicus Q4L208 575 64590 S486 S K K D V N L S K T E K M G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ75 574 64115 S485 N K K D V N L S K T E K M G N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001008586 637 70628 S546 S K K D I N L S K T E K M G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397447 653 73165 S510 K D K E V S L S K T R E W G Q
Nematode Worm Caenorhab. elegans P35449 667 75263 K573 T P K D L Q L K R F M E S G E
Sea Urchin Strong. purpuratus XP_784010 626 68574 S537 S K K E I S L S K T E E M G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 T448 V V G D S H D T S L G D G F E
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 I519 N L L N G S S I Q T D L G P Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77 28.9 98.9 N.A. 95.6 95.1 N.A. N.A. 92 N.A. 77.5 N.A. N.A. 52.3 25.3 55.7
Protein Similarity: 100 77 36.8 99.3 N.A. 97.2 97 N.A. N.A. 95.5 N.A. 84.6 N.A. N.A. 67 45.7 69.9
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. N.A. 100 N.A. 86.6 N.A. N.A. 46.6 26.6 60
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 66.6 46.6 100
Percent
Protein Identity: N.A. N.A. N.A. 32.7 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. 50 48.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 70 0 0 8 0 0 0 8 8 0 0 0 % D
% Glu: 0 0 0 16 0 0 0 0 0 0 62 24 0 0 16 % E
% Phe: 0 0 0 0 0 0 8 8 0 8 0 0 0 8 0 % F
% Gly: 0 0 8 8 8 0 0 0 0 0 8 8 16 77 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 16 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 8 62 77 0 0 0 0 8 70 0 0 54 0 0 0 % K
% Leu: 0 8 8 0 8 0 77 0 0 8 0 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 8 0 62 0 0 % M
% Asn: 39 0 0 8 0 54 0 0 0 0 0 0 8 0 54 % N
% Pro: 0 8 0 0 8 8 0 0 8 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % R
% Ser: 31 0 0 0 8 24 8 70 8 0 0 0 8 0 8 % S
% Thr: 8 0 0 0 0 0 0 8 0 77 0 0 0 8 0 % T
% Val: 8 8 8 0 54 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _