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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A8
All Species:
26.67
Human Site:
Y518
Identified Species:
48.89
UniProt:
Q9Y2E8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2E8
NP_056081.1
581
65422
Y518
E
E
E
Y
E
A
H
Y
I
R
R
Q
D
L
K
Chimpanzee
Pan troglodytes
XP_514716
751
84176
Y688
E
E
E
Y
E
A
H
Y
I
R
R
Q
D
L
K
Rhesus Macaque
Macaca mulatta
XP_001103158
318
36448
R257
E
Y
E
A
H
Y
I
R
R
Q
D
L
K
G
F
Dog
Lupus familis
XP_854123
580
65250
Y517
E
E
E
Y
E
A
H
Y
I
R
R
Q
D
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4D1
576
64718
Y513
E
E
E
Y
E
A
H
Y
I
R
Q
Q
D
L
K
Rat
Rattus norvegicus
Q4L208
575
64590
Y512
E
E
E
Y
E
A
H
Y
I
R
Q
Q
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ75
574
64115
Y511
E
G
E
Y
E
A
Q
Y
I
K
R
Q
D
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008586
637
70628
I572
E
E
E
Y
E
A
Q
I
Y
Q
R
Q
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397447
653
73165
F536
E
E
E
I
E
V
S
F
L
Q
S
R
I
R
G
Nematode Worm
Caenorhab. elegans
P35449
667
75263
E599
L
L
D
R
K
L
H
E
M
N
R
P
S
V
Q
Sea Urchin
Strong. purpuratus
XP_784010
626
68574
Y563
E
E
E
Y
E
V
N
Y
I
R
P
G
L
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
S474
D
E
D
T
P
P
G
S
G
F
R
T
K
L
R
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
K545
Q
F
A
V
S
S
N
K
N
L
P
N
N
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
28.9
98.9
N.A.
95.6
95.1
N.A.
N.A.
92
N.A.
77.5
N.A.
N.A.
52.3
25.3
55.7
Protein Similarity:
100
77
36.8
99.3
N.A.
97.2
97
N.A.
N.A.
95.5
N.A.
84.6
N.A.
N.A.
67
45.7
69.9
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
73.3
N.A.
N.A.
26.6
13.3
53.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
53.3
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
54
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
0
0
0
0
0
8
0
54
0
0
% D
% Glu:
77
70
77
0
70
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
8
0
8
0
0
8
0
8
16
% G
% His:
0
0
0
0
8
0
47
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
54
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
8
0
0
16
8
54
% K
% Leu:
8
8
0
0
0
8
0
0
8
8
0
8
8
62
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
8
8
0
8
8
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
16
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
16
0
0
24
16
54
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
8
8
47
54
8
0
8
8
% R
% Ser:
0
0
0
0
8
8
8
8
0
0
8
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
0
16
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
62
0
8
0
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _