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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRF All Species: 28.48
Human Site: S587 Identified Species: 62.67
UniProt: Q9Y2G1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2G1 NP_001120864.1 1151 124397 S587 M G S L M H P S D L R A K E H
Chimpanzee Pan troglodytes XP_522467 910 101904 D362 K K G K P N P D Q R Y F M L V
Rhesus Macaque Macaca mulatta XP_001116657 1151 124332 S587 M G S L M H P S D L R A K E H
Dog Lupus familis XP_540915 1147 124017 S583 M G S L M H P S D L R A K E H
Cat Felis silvestris
Mouse Mus musculus Q3UR85 1138 123269 S587 M G S L M H P S D L R A K E H
Rat Rattus norvegicus NP_001163958 1142 123486 S586 M G S L M H P S D L R A K E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512136 826 91357 N278 V K I E L P G N Q L T K V T L
Chicken Gallus gallus XP_420899 1434 155147 S834 M G S L M H P S D V R V K E D
Frog Xenopus laevis Q66IV1 1092 120762 V543 A L V V H G N V K I M G S L M
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611893 1423 155920 S607 S G H I V Q P S D S R A K Q E
Honey Bee Apis mellifera XP_393650 1170 130209 S567 T G H I V Q P S D A R A K Q N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.4 98 91.7 N.A. 88.7 88.9 N.A. 36.1 54.8 59.2 N.A. N.A. 29.6 34.7 N.A. N.A.
Protein Similarity: 100 51.9 99 94.2 N.A. 92.4 92.7 N.A. 48.2 63.2 70.9 N.A. N.A. 42.5 49.5 N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 80 0 N.A. N.A. 46.6 46.6 N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 26.6 86.6 13.3 N.A. N.A. 66.6 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 10 0 64 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 73 0 0 0 0 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 55 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 73 10 0 0 10 10 0 0 0 0 10 0 0 0 % G
% His: 0 0 19 0 10 55 0 0 0 0 0 0 0 0 46 % H
% Ile: 0 0 10 19 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 10 19 0 10 0 0 0 0 10 0 0 10 73 0 0 % K
% Leu: 0 10 0 55 10 0 0 0 0 55 0 0 0 19 10 % L
% Met: 55 0 0 0 55 0 0 0 0 0 10 0 10 0 10 % M
% Asn: 0 0 0 0 0 10 10 10 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 10 10 82 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 19 0 0 0 0 19 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 73 0 0 0 0 % R
% Ser: 10 0 55 0 0 0 0 73 0 10 0 0 10 0 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % T
% Val: 10 0 10 10 19 0 0 10 0 10 0 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _