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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRF All Species: 13.33
Human Site: S725 Identified Species: 29.33
UniProt: Q9Y2G1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2G1 NP_001120864.1 1151 124397 S725 T G S S G A F S H A G S Q F S
Chimpanzee Pan troglodytes XP_522467 910 101904 F485 E Y D Y K P E F A S A M G I N
Rhesus Macaque Macaca mulatta XP_001116657 1151 124332 S725 T G S S G A F S H A G S Q F S
Dog Lupus familis XP_540915 1147 124017 S721 T G S S G A F S H A G S Q F S
Cat Felis silvestris
Mouse Mus musculus Q3UR85 1138 123269 L712 K L A K L R R L D S L K S T G
Rat Rattus norvegicus NP_001163958 1142 123486 S716 R R L D S L K S T G S S G A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512136 826 91357 K401 Y P S D S R A K Q N I Q E V D
Chicken Gallus gallus XP_420899 1434 155147 S971 T V S S G A F S Q T G S Q F S
Frog Xenopus laevis Q66IV1 1092 120762 E666 E T R I D E L E R W S H K L A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611893 1423 155920 V880 A V L T K P Q V S S G Q Q Q L
Honey Bee Apis mellifera XP_393650 1170 130209 I706 S I S T I S S I S S N K Y S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.4 98 91.7 N.A. 88.7 88.9 N.A. 36.1 54.8 59.2 N.A. N.A. 29.6 34.7 N.A. N.A.
Protein Similarity: 100 51.9 99 94.2 N.A. 92.4 92.7 N.A. 48.2 63.2 70.9 N.A. N.A. 42.5 49.5 N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 0 13.3 N.A. 6.6 80 0 N.A. N.A. 13.3 13.3 N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 13.3 13.3 N.A. 13.3 80 13.3 N.A. N.A. 26.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 37 10 0 10 28 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 19 10 0 0 0 10 0 0 0 0 0 10 % D
% Glu: 19 0 0 0 0 10 10 10 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 37 10 0 0 0 0 0 37 10 % F
% Gly: 0 28 0 0 37 0 0 0 0 10 46 0 19 0 10 % G
% His: 0 0 0 0 0 0 0 0 28 0 0 10 0 0 0 % H
% Ile: 0 10 0 10 10 0 0 10 0 0 10 0 0 10 0 % I
% Lys: 10 0 0 10 19 0 10 10 0 0 0 19 10 0 0 % K
% Leu: 0 10 19 0 10 10 10 10 0 0 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % N
% Pro: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 19 0 0 19 46 10 0 % Q
% Arg: 10 10 10 0 0 19 10 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 55 37 19 10 10 46 19 37 19 46 10 10 46 % S
% Thr: 37 10 0 19 0 0 0 0 10 10 0 0 0 10 0 % T
% Val: 0 19 0 0 0 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 10 10 0 10 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _