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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5F
All Species:
30
Human Site:
S576
Identified Species:
66
UniProt:
Q9Y2H2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2H2
NP_055752.1
1132
128407
S576
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Chimpanzee
Pan troglodytes
XP_508074
1133
128517
S576
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Rhesus Macaque
Macaca mulatta
XP_001099262
1133
128209
S576
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Dog
Lupus familis
XP_535034
1137
128796
S580
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDA1
1132
127590
S576
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Rat
Rattus norvegicus
Q9ES21
587
67020
T54
D
V
P
P
S
A
V
T
R
P
I
Y
G
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514944
750
86937
Q217
F
W
N
K
Y
M
L
Q
D
L
I
E
I
G
N
Chicken
Gallus gallus
XP_421792
1126
127898
S576
P
V
T
E
D
L
Y
S
I
F
T
K
E
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8E7C5
1120
126036
S576
P
V
T
E
D
L
Y
S
I
F
S
K
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392092
1118
126657
Q582
V
V
N
E
E
V
F
Q
E
R
T
E
E
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789035
2077
234760
T598
Q
E
I
Q
E
D
L
T
L
I
D
E
Q
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.8
N.A.
90.5
21.2
N.A.
62.1
82.9
N.A.
71.2
N.A.
N.A.
35.3
N.A.
26.6
Protein Similarity:
100
99.9
99.1
95
N.A.
94.5
33.8
N.A.
64.4
90.2
N.A.
82.8
N.A.
N.A.
53.6
N.A.
38.4
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
100
N.A.
93.3
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
100
N.A.
100
N.A.
N.A.
66.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
64
10
0
0
10
0
10
0
0
0
10
% D
% Glu:
0
10
0
73
19
0
0
0
10
0
0
28
73
10
64
% E
% Phe:
10
0
0
0
0
0
10
0
0
64
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
64
10
19
0
10
10
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
64
0
73
0
% K
% Leu:
0
0
0
0
0
64
19
0
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
64
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
19
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
64
0
0
10
0
0
0
0
% S
% Thr:
0
0
64
0
0
0
0
19
0
0
64
0
0
0
0
% T
% Val:
10
82
0
0
0
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
64
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _