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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5F
All Species:
22.12
Human Site:
S668
Identified Species:
48.67
UniProt:
Q9Y2H2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2H2
NP_055752.1
1132
128407
S668
V
N
Q
Y
Q
R
L
S
L
E
N
L
E
K
I
Chimpanzee
Pan troglodytes
XP_508074
1133
128517
S668
V
N
Q
Y
Q
R
L
S
L
E
N
L
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001099262
1133
128209
S668
V
N
Q
Y
Q
R
L
S
L
E
D
L
E
K
I
Dog
Lupus familis
XP_535034
1137
128796
S672
V
N
Q
Y
Q
R
L
S
L
E
D
L
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDA1
1132
127590
G668
V
N
Q
Y
Q
R
L
G
L
E
D
L
E
R
I
Rat
Rattus norvegicus
Q9ES21
587
67020
D138
F
Y
F
S
T
T
Y
D
L
T
H
T
L
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514944
750
86937
N301
K
R
R
G
V
D
K
N
G
N
V
A
N
Y
V
Chicken
Gallus gallus
XP_421792
1126
127898
S668
V
N
Q
Y
Q
R
L
S
L
E
A
L
E
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8E7C5
1120
126036
S668
V
N
Q
Y
Q
R
L
S
L
E
G
L
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392092
1118
126657
P666
V
T
N
Y
Q
R
V
P
L
E
D
I
V
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789035
2077
234760
P694
I
T
Q
Y
E
R
I
P
I
D
A
M
T
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.8
N.A.
90.5
21.2
N.A.
62.1
82.9
N.A.
71.2
N.A.
N.A.
35.3
N.A.
26.6
Protein Similarity:
100
99.9
99.1
95
N.A.
94.5
33.8
N.A.
64.4
90.2
N.A.
82.8
N.A.
N.A.
53.6
N.A.
38.4
P-Site Identity:
100
100
93.3
93.3
N.A.
80
6.6
N.A.
0
93.3
N.A.
93.3
N.A.
N.A.
46.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
20
93.3
N.A.
93.3
N.A.
N.A.
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
19
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
10
37
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
73
0
0
64
0
0
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
10
0
0
10
0
0
73
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
0
0
55
0
% K
% Leu:
0
0
0
0
0
0
64
0
82
0
0
64
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
64
10
0
0
0
0
10
0
10
19
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% P
% Gln:
0
0
73
0
73
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
10
0
0
82
0
0
0
0
0
0
0
10
10
% R
% Ser:
0
0
0
10
0
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
19
0
0
10
10
0
0
0
10
0
10
10
0
0
% T
% Val:
73
0
0
0
10
0
10
0
0
0
10
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
82
0
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _