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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5F All Species: 22.12
Human Site: S668 Identified Species: 48.67
UniProt: Q9Y2H2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2H2 NP_055752.1 1132 128407 S668 V N Q Y Q R L S L E N L E K I
Chimpanzee Pan troglodytes XP_508074 1133 128517 S668 V N Q Y Q R L S L E N L E K I
Rhesus Macaque Macaca mulatta XP_001099262 1133 128209 S668 V N Q Y Q R L S L E D L E K I
Dog Lupus familis XP_535034 1137 128796 S672 V N Q Y Q R L S L E D L E K I
Cat Felis silvestris
Mouse Mus musculus Q8CDA1 1132 127590 G668 V N Q Y Q R L G L E D L E R I
Rat Rattus norvegicus Q9ES21 587 67020 D138 F Y F S T T Y D L T H T L Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514944 750 86937 N301 K R R G V D K N G N V A N Y V
Chicken Gallus gallus XP_421792 1126 127898 S668 V N Q Y Q R L S L E A L E K I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A8E7C5 1120 126036 S668 V N Q Y Q R L S L E G L E K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392092 1118 126657 P666 V T N Y Q R V P L E D I V L I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789035 2077 234760 P694 I T Q Y E R I P I D A M T A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 91.8 N.A. 90.5 21.2 N.A. 62.1 82.9 N.A. 71.2 N.A. N.A. 35.3 N.A. 26.6
Protein Similarity: 100 99.9 99.1 95 N.A. 94.5 33.8 N.A. 64.4 90.2 N.A. 82.8 N.A. N.A. 53.6 N.A. 38.4
P-Site Identity: 100 100 93.3 93.3 N.A. 80 6.6 N.A. 0 93.3 N.A. 93.3 N.A. N.A. 46.6 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. 20 93.3 N.A. 93.3 N.A. N.A. 66.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 19 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 10 0 10 37 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 73 0 0 64 0 0 % E
% Phe: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 10 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 10 0 0 10 0 0 73 % I
% Lys: 10 0 0 0 0 0 10 0 0 0 0 0 0 55 0 % K
% Leu: 0 0 0 0 0 0 64 0 82 0 0 64 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 64 10 0 0 0 0 10 0 10 19 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % P
% Gln: 0 0 73 0 73 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 10 10 0 0 82 0 0 0 0 0 0 0 10 10 % R
% Ser: 0 0 0 10 0 0 0 55 0 0 0 0 0 0 0 % S
% Thr: 0 19 0 0 10 10 0 0 0 10 0 10 10 0 0 % T
% Val: 73 0 0 0 10 0 10 0 0 0 10 0 10 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 82 0 0 10 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _