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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5F All Species: 22.73
Human Site: S752 Identified Species: 50
UniProt: Q9Y2H2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2H2 NP_055752.1 1132 128407 S752 E K K L E R K S S K P H E D I
Chimpanzee Pan troglodytes XP_508074 1133 128517 S752 E K K L E R K S S K P H E D I
Rhesus Macaque Macaca mulatta XP_001099262 1133 128209 S752 E K K L E R K S S K P H E D I
Dog Lupus familis XP_535034 1137 128796 S756 E K K L E R K S S K P H E D I
Cat Felis silvestris
Mouse Mus musculus Q8CDA1 1132 127590 S752 E K K L E R K S S K P H E D I
Rat Rattus norvegicus Q9ES21 587 67020 R222 S C F R A G V R Y Y V R G I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514944 750 86937 K385 V D Q A G R E K I I G D A Y L
Chicken Gallus gallus XP_421792 1126 127898 S752 E K K L E R K S S K P H E D I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A8E7C5 1120 126036 H752 E K K L E R R H S K P H E D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392092 1118 126657 L750 V A M D I S N L P K I P I A M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789035 2077 234760 K778 E D K M E K K K S R V S Q E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 91.8 N.A. 90.5 21.2 N.A. 62.1 82.9 N.A. 71.2 N.A. N.A. 35.3 N.A. 26.6
Protein Similarity: 100 99.9 99.1 95 N.A. 94.5 33.8 N.A. 64.4 90.2 N.A. 82.8 N.A. N.A. 53.6 N.A. 38.4
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 100 N.A. 86.6 N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 26.6 100 N.A. 93.3 N.A. N.A. 13.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 0 0 0 0 0 10 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 10 0 0 0 0 0 0 0 10 0 64 10 % D
% Glu: 73 0 0 0 73 0 10 0 0 0 0 0 64 10 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 0 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 64 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 10 10 10 0 10 10 64 % I
% Lys: 0 64 73 0 0 10 64 19 0 73 0 0 0 0 0 % K
% Leu: 0 0 0 64 0 0 0 10 0 0 0 0 0 0 10 % L
% Met: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 64 10 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 73 10 10 0 10 0 10 0 0 0 % R
% Ser: 10 0 0 0 0 10 0 55 73 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 19 0 0 0 0 0 10 0 0 0 19 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _