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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NISCH
All Species:
10.91
Human Site:
S521
Identified Species:
40
UniProt:
Q9Y2I1
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2I1
NP_009115.2
1504
166643
S521
V
Q
E
E
A
L
A
S
S
L
S
S
T
D
S
Chimpanzee
Pan troglodytes
XP_001152331
923
102828
A64
D
S
L
E
S
I
P
A
G
Q
A
A
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001085527
1382
152035
D485
V
T
T
E
K
E
L
D
T
V
E
V
L
K
A
Dog
Lupus familis
XP_533798
1528
169055
S522
V
Q
E
E
A
L
A
S
S
L
S
S
T
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80TM9
1593
174993
S523
Q
E
E
A
L
A
S
S
L
S
S
T
D
S
L
Rat
Rattus norvegicus
Q4G017
1502
166484
S522
V
Q
E
E
A
L
A
S
S
L
S
S
T
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791237
1173
132152
V313
L
A
K
L
Y
S
L
V
K
L
D
V
R
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
88
89.3
N.A.
85.1
89.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.2
Protein Similarity:
100
60.1
88.7
92.5
N.A.
88.8
93.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
13.3
13.3
100
N.A.
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
53.3
33.3
100
N.A.
40
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
43
15
43
15
0
0
15
15
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
15
0
0
15
0
15
58
15
% D
% Glu:
0
15
58
72
0
15
0
0
0
0
15
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
15
0
0
0
15
0
0
0
0
15
0
% K
% Leu:
15
0
15
15
15
43
29
0
15
58
0
0
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% P
% Gln:
15
43
0
0
0
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% R
% Ser:
0
15
0
0
15
15
15
58
43
15
58
43
15
29
43
% S
% Thr:
0
15
15
0
0
0
0
0
15
0
0
15
43
0
0
% T
% Val:
58
0
0
0
0
0
0
15
0
15
0
29
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _