KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NISCH
All Species:
17.27
Human Site:
Y1390
Identified Species:
63.33
UniProt:
Q9Y2I1
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2I1
NP_009115.2
1504
166643
Y1390
L
D
E
D
C
V
H
Y
P
L
P
E
F
A
K
Chimpanzee
Pan troglodytes
XP_001152331
923
102828
E817
P
L
P
E
F
A
K
E
P
P
Q
R
D
R
Y
Rhesus Macaque
Macaca mulatta
XP_001085527
1382
152035
Y1268
L
D
E
D
C
I
H
Y
P
L
P
E
F
A
K
Dog
Lupus familis
XP_533798
1528
169055
Y1414
L
D
E
D
F
V
H
Y
P
L
P
D
F
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80TM9
1593
174993
Y1479
L
D
E
D
Y
I
H
Y
P
L
P
E
F
A
K
Rat
Rattus norvegicus
Q4G017
1502
166484
Y1388
L
D
E
D
Y
I
H
Y
P
L
P
E
F
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791237
1173
132152
N1067
H
V
C
Y
P
I
P
N
F
S
K
L
L
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
88
89.3
N.A.
85.1
89.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.2
Protein Similarity:
100
60.1
88.7
92.5
N.A.
88.8
93.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
0
0
0
72
0
% A
% Cys:
0
0
15
0
29
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
72
0
72
0
0
0
0
0
0
0
15
15
0
0
% D
% Glu:
0
0
72
15
0
0
0
15
0
0
0
58
0
0
15
% E
% Phe:
0
0
0
0
29
0
0
0
15
0
0
0
72
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
0
0
15
0
0
0
72
% K
% Leu:
72
15
0
0
0
0
0
0
0
72
0
15
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
15
0
15
0
15
0
15
0
86
15
72
0
0
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
15
0
0
0
29
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
29
0
0
72
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _