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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NINL All Species: 15.15
Human Site: S148 Identified Species: 30.3
UniProt: Q9Y2I6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2I6 NP_079452.3 1382 156344 S148 W R S A S L E S V E S P K S D
Chimpanzee Pan troglodytes XP_001150168 1409 159133 S166 W R S A S L E S V E S L K S D
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 E312 T V I E P L D E E A R P S H I
Dog Lupus familis XP_534204 1476 166548 L196 P L R R S A S L E S V E S L K
Cat Felis silvestris
Mouse Mus musculus Q6ZQ12 1394 157820 S149 R R S A S L E S V E S L K S D
Rat Rattus norvegicus XP_230778 1394 157847 S149 R R S A S L E S V E S L K S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 S140 A R A S H I P S S D R R E H W
Chicken Gallus gallus XP_426482 2171 248500 L219 E V T V L E P L G E E V Q P A
Frog Xenopus laevis NP_001086424 1836 213151 L149 Q L K R S S S L E S V E S L K
Zebra Danio Brachydanio rerio XP_700610 1713 199360 D139 D E D A Q E S D D R T V P R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11929 741 84355
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 Y160 E L G P M K S Y H E S T E Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 24.6 59.3 N.A. 58.3 59.4 N.A. 28.3 26.4 36.9 26.2 N.A. 21.3 N.A. N.A. 27.6
Protein Similarity: 100 95.8 38.7 70.1 N.A. 72.1 72.4 N.A. 42.7 41.1 51.7 45 N.A. 36.1 N.A. N.A. 49.2
P-Site Identity: 100 93.3 13.3 6.6 N.A. 86.6 86.6 N.A. 13.3 6.6 6.6 6.6 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 93.3 20 6.6 N.A. 86.6 86.6 N.A. 46.6 20 6.6 13.3 N.A. 0 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 42 0 9 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 9 9 9 9 0 0 0 0 34 % D
% Glu: 17 9 0 9 0 17 34 9 25 50 9 17 17 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 9 0 0 0 0 17 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 9 0 0 9 0 0 0 0 0 0 34 0 25 % K
% Leu: 0 25 0 0 9 42 0 25 0 0 0 25 0 17 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 9 9 0 17 0 0 0 0 17 9 9 0 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 0 9 9 0 % Q
% Arg: 17 42 9 17 0 0 0 0 0 9 17 9 0 9 0 % R
% Ser: 0 0 34 9 50 9 34 42 9 17 42 0 25 34 9 % S
% Thr: 9 0 9 0 0 0 0 0 0 0 9 9 0 0 0 % T
% Val: 0 17 0 9 0 0 0 0 34 0 17 17 0 0 0 % V
% Trp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _