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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NINL All Species: 15.45
Human Site: S189 Identified Species: 30.91
UniProt: Q9Y2I6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2I6 NP_079452.3 1382 156344 S189 D F G S P Q K S C S P S F D T
Chimpanzee Pan troglodytes XP_001150168 1409 159133 S207 D F G S P Q K S C S P S F D T
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 G356 D L N A S Q S G S S P P Q D W
Dog Lupus familis XP_534204 1476 166548 P239 V F E C L H K P S S L S L D T
Cat Felis silvestris
Mouse Mus musculus Q6ZQ12 1394 157820 S190 V F G T L R K S C S P S F S T
Rat Rattus norvegicus XP_230778 1394 157847 S190 V F G T P R K S C S P S F N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 Q180 Q S V S P P T Q D W I E E K L
Chicken Gallus gallus XP_426482 2171 248500 T265 D L N A S Q G T S L P T P E W
Frog Xenopus laevis NP_001086424 1836 213151 N192 I F D G R R R N S S P C S D M
Zebra Danio Brachydanio rerio XP_700610 1713 199360 G179 D E P T T P R G K A L S L C D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11929 741 84355
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 S228 G Q M N A S M S V Y E Q G P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 24.6 59.3 N.A. 58.3 59.4 N.A. 28.3 26.4 36.9 26.2 N.A. 21.3 N.A. N.A. 27.6
Protein Similarity: 100 95.8 38.7 70.1 N.A. 72.1 72.4 N.A. 42.7 41.1 51.7 45 N.A. 36.1 N.A. N.A. 49.2
P-Site Identity: 100 100 33.3 40 N.A. 66.6 73.3 N.A. 13.3 20 26.6 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 40 40 N.A. 80 93.3 N.A. 13.3 46.6 46.6 33.3 N.A. 0 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 9 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 34 0 0 9 0 9 0 % C
% Asp: 42 0 9 0 0 0 0 0 9 0 0 0 0 42 9 % D
% Glu: 0 9 9 0 0 0 0 0 0 0 9 9 9 9 0 % E
% Phe: 0 50 0 0 0 0 0 0 0 0 0 0 34 0 0 % F
% Gly: 9 0 34 9 0 0 9 17 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 42 0 9 0 0 0 0 9 0 % K
% Leu: 0 17 0 0 17 0 0 0 0 9 17 0 17 0 9 % L
% Met: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 17 9 0 0 0 9 0 0 0 0 0 9 0 % N
% Pro: 0 0 9 0 34 17 0 9 0 0 59 9 9 9 0 % P
% Gln: 9 9 0 0 0 34 0 9 0 0 0 9 9 0 0 % Q
% Arg: 0 0 0 0 9 25 17 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 25 17 9 9 42 34 59 0 50 9 9 9 % S
% Thr: 0 0 0 25 9 0 9 9 0 0 0 9 0 0 42 % T
% Val: 25 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 17 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _